Protein Alignment Cyp4d21 and Cyp24a1

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_034126.1
• Gene: Cyp24a1 / 13081
• MGIID: 88593
• Length: 514
• Species: Mus musculus
• Alignment Length: 503
• Identity: 120/503 - (23%)
• Similarity: 209/503 - (41%)
• Gaps: 117/503 - (23%)

  Fly    35 GPFTIPIVGNGLQAL---TLRPENFIQRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESI-LSS 95
            ||...|::|:.|:..   .|:.::  ....:|..|||:.||:           .|..|:|: |.|
Mouse    60 GPTNWPLLGSLLEIFWKGGLKKQH--DTLAEYHKKYGQIFRM-----------KLGSFDSVHLGS 111

  Fly    96 STLL------KKAHLYRF-------LRDFLGD--GLLLSTGNKW-----TSRRKVLAPAFHFK-- 138
            .:||      :.||..|.       .||...:  ||::..|.:|     ..::|::.|....|
Mouse   112 PSLLEALYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLD 176

  Fly   139 -----CLENFV----EIMDRNSGI--MVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVN 192
                 .|.:|:    |:.|....|  :..:|..::....|:.|:            |...|:...
Mouse   177 KKINEVLADFMGQIDELRDERGRIQDLYSELNKWSFESICLVLY------------EKRFGLLQK 229

  Fly   193 AQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFT---DKVIR 254
            ...|....:..|:|:::....|.:.:         |:.   :::||  :..:.|..|   |.:.:
Mouse   230 DTEEEALTFIAAIKTMMSTFGKMMVT---------PVE---LHKRL--NTKVWQAHTLAWDTIFK 280

  Fly   255 ERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDIREEVDVFIFAGDD 319
            ..:..::......:.:|   |.|        .|.||..|..:..|     ::...|.....|..:
Mouse   281 SVKPCIDHRLERYSQQP---GAD--------FLCDIYQQDHLSKK-----ELYAAVTELQLAAVE 329

  Fly   320 TTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLE----LKYLDCVIKETMRLH 380
            ||.:.:...|:.:||:|:||:.:..|:.|||   ||   .||...|    :.||...:||:|||.
Mouse   330 TTANSLMWILYNLSRNPQVQQRLLREIQSVL---PD---NQTPRAEDVRNMPYLKACLKESMRLT 388

  Fly   381 PPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLA 445
            |.||...|.:.:...:||.|:|..|.:.|....:....:.|.|...|:||||::.:...|  |.|
Mouse   389 PSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQVLGSSEDNFEDADKFRPERWLEKEKKIN--PFA 451

  Fly   446 YIPFSSGPKNCIGQKFANLQMKALISKVIRHY----------ELLPLG 483
            ::||..|.:.|||::.|.||:...:..:|:.|          |:|.||
Mouse   452 HLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATDSEPVEMLHLG 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	111/467 (24%)
Cyp24a1	NP_034126.1	CYP24A1	90..508	CDD:410738	113/471 (24%)