Protein Alignment Cyp4d21 and CYP4F22

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 144/455 - (31%)
• Similarity: 227/455 - (49%)
• Gaps: 68/455 - (14%)

  Fly    72 RLWILGECLIY------TKDLK---------------------------YFESILSSSTLL--KK 101
            |.|:||...:|      .:|.|                           |.:.:|.:|..:  |.
Human    65 RNWLLGHLGMYLPNEAGLQDEKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKD 129

  Fly   102 AHLYRFLRDFLGDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGK- 165
            ...|.||:.:||||||||.|:||:..|::|.|||||..|:.:::|.::::.||..|.::.|:|.
Human   130 DLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSA 194

  Fly   166 TCVDLFKFVSLEALDVTTETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLA 230
            ..:|:|:.:||..||...:.......|.| |....|..|:     ||   |:::|:|..:.....
Human   195 VSLDMFEHISLMTLDSLQKCVFSYNSNCQ-EKMSDYISAI-----IE---LSALSVRRQYRLHHY 250

  Fly   231 APLVY------RRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTL-- 287
            ...:|      ||.::...::..||.:||:|||..|.:..|:...|          .|...||
Human   251 LDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQQGAEAWLK----------AKQGKTLDF 305

  Fly   288 LDILLQA-TIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLG 351
            :|:||.| ..|.|.|||.|||.|.|.|:|.|.|||:||:|..|..::::|:.||...||:..|:.
Human   306 IDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMK 370

  Fly   352 PDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKI--GEITIPGNTSILLMPYYV 414
            ......:....|.:|.:....|||::|.:|||.::.|...||:|:  |.| ||.....|:..|..
Human   371 GRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGT 434

  Fly   415 YRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYEL 479
            :.:|..:||..|:.|.|: |........||||:|||:||:|||||.||..:::.:::..:..:.|
Human   435 HHNPTVWPDSKVYNPYRF-DPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRL 498

  Fly   480  479
            Human   499  498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	144/455 (32%)
CYP4F22	NP_775754.2	p450	60..524	CDD:278495	144/455 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154631
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D214327at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750