Protein Alignment Cyp4d21 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 494
• Identity: 182/494 - (36%)
• Similarity: 276/494 - (55%)
• Gaps: 57/494 - (11%)

  Fly    40 PIVGNGLQALTLRPENFIQRFGDYFNK---YGKTFR------LWILGECLIYTKDLKYFESILSS 95
            |:||:   ||.::|.|     .::|.:   |.:.||      |||....|:.....:..|.||:|
Mouse    58 PLVGH---ALYMKPNN-----AEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTS 114

  Fly    96 STLLKKAHLYRFLRDFLGDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKN 160
            |..:.|:.||:||:.:||.|||.|||:||.:|||:|.|.|||..||||:::|:..:.|:|.||:.
Mouse   115 SKQIDKSFLYKFLQPWLGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEK 179

  Fly   161 YADGKTCVDLFKFVSLEALDVTTETAMGVQVNAQNEPNFPYTKA---LKSVVYIESKRLASVSMR 222
            :.: :...:.|.:::|.|||:..|||||..:.||:..:..|.:.   :..::|   :|     |:
Mouse   180 HVN-QEAFNCFFYITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIY---RR-----MK 235

  Fly   223 YNWLFPLAAPLVY---RRLQKDIAIMQDFTDKVIRERRAILER-ARADGTYKPLIMGDDDIGGKA 283
            ..||:.....||:   |..::.:..:..||:.||.||  :.|| |..|.|.    .|...|..|.
Mouse   236 MPWLWFDLWYLVFKEGRDHKRGLKCLHTFTNNVIAER--VKERKAEEDWTG----AGRGPIPSKN 294

  Fly   284 K-MTLLDILLQAT-IDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEEL 346
            | ...||:||..| .:...||..|||||||.|:|.|.|||.:.::.:|:.:..:|:||..:.:||
Mouse   295 KRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQEL 359

  Fly   347 VSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMP 411
            ..|.|.. ...||...|.:|||||||||||:|:.|.||:..|.:.||.::|...:...|..:::|
Mouse   360 DEVFGRS-HRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGGYKVTKGTEAIIIP 423

  Fly   412 YYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRH 476
            |.::|||.|||||..|:|||:.. :.:....|.||:|||:||:||||||||.::.|.:::.::|.
Mouse   424 YALHRDPRYFPDPEEFRPERFFP-ENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQ 487

  Fly   477 Y--------ELLPLGADLKATYTFILSSSTGNNVGLKPR 507
            :        |.|.|..||      ||..:.|..:.||.|
Mouse   488 FWVESNQKREELGLAGDL------ILRPNNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	170/456 (37%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	171/461 (37%)