Protein Alignment Cyp4d21 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 547
• Identity: 141/547 - (25%)
• Similarity: 238/547 - (43%)
• Gaps: 100/547 - (18%)

  Fly     2 WILLGIAVLI----------------MTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALT 50
            |:..|..::|                |.|.:|:              |.||.....:...:..|:
 Frog    12 WVYSGFLLIIIGAVVAFLAYCAYIKYMHLKYDD--------------IPGPPRDSFLLGHIPTLS 62

  Fly    51 LRPENFI---QRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYR-----F 107
            ...||:.   ..|..:...||..|::.||...:||:...:..:..|.||...|..:.|.     |
 Frog    63 KAEENYSVVHDLFLHWAEIYGPVFKINILHRVMIYSTSPESVKECLMSSKYPKDPYTYNQLFNLF 127

  Fly   108 LRDFLGDGLLLSTG-NKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLF 171
            .:.|||.|||.... :.|..:|:::.|||....|:..:.|.:..:..|:|||:..|||...|.:.
 Frog   128 GKRFLGKGLLTDPDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEKADGHQEVSMH 192

  Fly   172 KFVSLEALDVTTETAMGVQVN--AQNEPNFPYTKALKSVVYIESKRLASVSMRY---NWLFPLAA 231
            ..::...|||.|:.|.|:.:.  ..|:.:||  .|:..|:....:.:.:..|:|   :|.|
 Frog   193 SIINRVTLDVITKVAFGMDLGLVEGNKTDFP--NAISKVLTGMMRYMQNPYMQYFPKHWAF---- 251

  Fly   232 PLVYRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATI 296
               .|.:|:...:::....:.|.:|:    :|..:|...|            |..|..||..|.:
 Frog   252 ---VREVQESADLLRKTGKECISQRK----KAMQNGEELP------------KDILTKILQCAEL 297

  Fly   297 DNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQT 361
            :| .|.|..:.:....|..||.:||.:.:|..:..::|.|::...:..|:..|:|...|  ::..
 Frog   298 EN-ALDDEIMLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVIGFKRD--ISYD 359

  Fly   362 KLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLV 426
            .:..|.|:..|:||::|.:||.|...||:.||.....|.|||..||....|.:.|..::|.||..
 Frog   360 DIQNLNYMTQVLKESLRFYPPGPGTSRYLKEDTIFEGIKIPGGVSITFNTYVMGRMEKFFQDPCK 424

  Fly   427 FKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIR--HYELLPLGADLKAT 489
            |.|||:   ...:..|...|.||:.||::|:||.|:.|:.|.::||:|:  .:||:|
 Frog   425 FDPERF---HPAAVKPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEFELVP-------- 478

  Fly   490 YTFILSSSTGNNVGLK------PRTRV 510
                     |.:.|:|      ||..|
 Frog   479 ---------GQSFGIKDTGTLRPRDGV 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	122/446 (27%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	129/473 (27%)