Protein Alignment Cyp4d21 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_031761583.1
• Gene: cyp26c1 / 100489980
• XenbaseID: XB-GENE-1219115
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 585
• Identity: 108/585 - (18%)
• Similarity: 191/585 - (32%)
• Gaps: 164/585 - (28%)

  Fly     3 ILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPF---TIPIVGNGLQALTLRPENFIQRFGDYF 64
            :||..:..:.:|.|.::|.:.......|..:..||   |:..:..|....:.|.|
 Frog    24 LLLAASHQLWSLRWHSTRDRGSSLPLPKGSMGWPFFGETLHWLVQGSSFHSSRRE---------- 78

  Fly    65 NKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLL-STGNKWTSRR 128
             |||..|:..:||:.:|.....:....||.....|......:..:..||...|. |.|.....:|
 Frog    79 -KYGNIFKTHLLGKPVIRVTGAENIRKILLGEHHLVSTQWPQSTQIILGSNTLSNSIGELHRQKR 142

  Fly   129 KVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVNA 193
            |:::.......||::   :.|....:..:::::..|...|.:..........:.....:|:
 Frog   143 KMMSKVLSSAALESY---LPRIHEAVRWEVRSWCRGVGPVSMLSCAKALTFRIAARILLGL---- 200

  Fly   194 QNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLV-YRRLQKDIAIMQDFTDKVIRERR 257
                      :|....:.|..|.....:...:..||..|.. .|:..|....:..:.::.|:|:
 Frog   201 ----------SLTDTQFQELTRTFEQLVENLFCLPLDIPFSGLRKGMKARDTLHQYMEEAIKEK- 254

  Fly   258 AILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATID-NKPLSDVDIREEVDVFIFAGDDTT 321
                          |...|.|    |....||.|:.:..: .|.::..:::|.....|||...||
 Frog   255 --------------LSKRDPD----ACEDALDYLINSAKEGGKEINMQELKESAIELIFAAFLTT 301

  Fly   322 TSGVSHALHAISRHPKVQECIYEELVS-------------------------------------- 348
            .|..:..:..:.:||.....|.:||.|
 Frog   302 ASASTSLVLLLLKHPSAIHKIRQELASHGLSEHCEQCLPATENPNNNILQDNGHQCLTAGCQLPL 366

  Fly   349 VLG---------------------PDPDAS----------------------------------- 357
            |:|                     .||..|
 Frog   367 VMGTEGQVKTLWEQTKQLLTDRTDQDPQNSLSSKNLVNGENRIQEAPCSHDKSNCSPVPGKLQNS 431

  Fly   358 ---------VTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYY 413
                     ::..||..|.|||||:||.:||.|||....|...:..::....||...|::    |
 Frog   432 VFEGTCQQNISLEKLKSLHYLDCVVKEVLRLLPPVSGGYRTALQTFELDGYQIPKGWSVM----Y 492

  Fly   414 VYRDPE----YFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVI 474
            ..||..    .:.:..:|.|||:...:.........||||..|.::|||::.|.:.:|.|..:::
 Frog   493 SIRDTHETAAVYQNAEMFDPERFSTERDEGKLGRFNYIPFGGGARSCIGKELAQIILKILAMELV 557

  Fly   475  474
             Frog   558  557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	94/517 (18%)
cyp26c1	XP_031761583.1	cytochrome_P450	59..588	CDD:477761	100/550 (18%)