DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d21 and LOC100488078

DIOPT Version :9

Sequence 1:	NP_609129.2	Gene:	Cyp4d21 / 34036	FlyBaseID:	FBgn0031925	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_012817051.1	Gene:	LOC100488078 / 100488078	-ID:	-	Length:	510	Species:	Xenopus tropicalis

Alignment Length:	450	Identity:	145/450 - (32%)
Similarity:	234/450 - (52%)	Gaps:	24/450 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 DYFNKYGKTFRLWI---LGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGNK 123
            :|..||...:.:|:   ....:|...|  |.::|||... .|....|.||..::|.|||:.:|.|
Frog    74 NYAKKYPYAYPMWLGNFFASLIICHPD--YAKAILSRQD-PKDDFGYYFLTPWIGKGLLVLSGQK 135

  Fly   124 WTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMG 188
            |...|::|.||||:..|:.:|::|...|.:|::|.......|..|:||..|||..||...:.|..
Frog   136 WFQHRRLLTPAFHYDVLKPYVKLMADCSNVMLDKWDKEISDKKPVELFHHVSLMTLDSIMKCAFS 200

  Fly   189 VQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVI 253
            ...|.||.....|.||:..:.|:...|...:....:::|.| :|..: |.::.:.:..|.|||||
Frog   201 YHSNCQNNSENKYIKAVYELSYLVDHRFTFLPYHSDFIFYL-SPHGF-RFRRALKVAHDHTDKVI 263

  Fly   254 RERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDN-KPLSDVDIREEVDVFIFAG 317
            ::|:..|.....          .:.|..|..:..|||||.|..:| |.|||.|:|.|||.|:|.|
Frog   264 KQRKKSLHEQNE----------LEKIQQKRHLDFLDILLCAKDENGKGLSDEDLRAEVDTFMFEG 318

  Fly   318 DDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPP 382
            .|||.||:|..|:.::::|:.|:...||:..|||  ...:|....|.::.|....|||::||:||
Frog   319 HDTTASGISWTLYCMAKYPEHQQKCREEIRDVLG--GKQTVDWDDLGKMPYTTLCIKESLRLYPP 381

  Fly   383 VPILGRYIPEDLKIGE-ITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAY 446
            ||.:.|.:.:.:...: .::|.::.:||..|.:.|....:.||.||.|.|: ..:.::.....|:
Frog   382 VPGIARQLTQPITFCDGRSLPKDSMVLLSLYAINRCSSIWEDPEVFDPMRF-SAENSAKRNSHAF 445

  Fly   447 IPFSSGPKNCIGQKFANLQMKALISKVIRHYELLP-LGADLKATYTFILSSSTGNNVGLK 505
            :|||:|.:|||||.||..:||..::..::.:||.| .|.:.......:|.|..|.::.||
Frog   446 LPFSAGSRNCIGQNFAMNEMKVALALTLQRFELFPDTGIEPLTAPQLVLRSLNGIHLKLK 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	139/425 (33%)
LOC100488078	XP_012817051.1	p450	48..502	CDD:278495	143/445 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D214327at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010