Protein Alignment Cyp4d21 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 491
• Identity: 141/491 - (28%)
• Similarity: 254/491 - (51%)
• Gaps: 46/491 - (9%)

  Fly     4 LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIP----IVGNGLQALTLRPENFIQRFGDYF 64
            :||:.:|::..|.....::|.:...::      |..|    ..|:.    ..:.|..::......
Mouse    24 VLGLLLLLVKAVQFYLHRKWLLKALQQ------FPSPPFHWFFGHE----QFKGEQELKEVVSCI 78

  Fly    65 NKYGKTFRLWILGE---CLIYTKDLKYFESILSSSTLLKKAH-LYRFLRDFLGDGLLLSTGNKWT 125
            ..:...|..|..|.   ..:|..|  |.:.||..|.  .||: :||.|..::|.||||..|..|.
Mouse    79 EHFPSAFPCWFWGSNAYLTVYDPD--YMKVILGRSD--PKANGIYRLLAPWIGYGLLLLNGQPWF 139

  Fly   126 SRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQ 190
            ..|::|.||||:..|:.:|:.|..:..:|::|.:..|...:.:::|:.:||..||...:.|...:
Mouse   140 QHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAGQDSSIEIFQHISLMTLDTVMKCAFSHK 204

  Fly   191 VNAQNEPNF-PYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIA-IMQDFTDKVI 253
            .:.|.:.|: .|.:|:..:..:...|:.::..:.:.::.|::   ..||.|... :..|.||.||
Mouse   205 GSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFHQNDTIYRLSS---NGRLAKQACQLAHDHTDGVI 266

  Fly   254 RERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDN-KPLSDVDIREEVDVFIFAG 317
            :.|:   ::.:.:|..       ::|..|.::..|||||.|.::| ..:||.|:|.|||.|:|.|
Mouse   267 KMRK---DQLQDEGEL-------ENIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEG 321

  Fly   318 DDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPP 382
            .|||.||||...:|::.||:.|:...||:.|:||  ..:|:|...|.::.|....|||.:||:||
Mouse   322 HDTTASGVSWIFYALATHPEHQQRCREEVQSLLG--DGSSITWDHLDQIPYTTMCIKEALRLYPP 384

  Fly   383 VPILGRYIPEDLKIGE-ITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWM-DMKTTSNTPPLA 445
            ||.:.|.:...:...: .::|....:.|..|.::.:|:.:|:|.||.|.|:. |....|:    :
Mouse   385 VPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSH----S 445

  Fly   446 YIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLP 481
            ::|||.|.:||||::||..::|.:::..:.|:||||
Mouse   446 FLPFSGGARNCIGKQFAMSELKVIVALTLLHFELLP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	132/423 (31%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	132/434 (30%)