Protein Alignment Spn28B and SERPINB11

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001357404.1
• Gene: SERPINB11 / 89778
• HGNCID: 14221
• Length: 392
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 111/401 - (27%)
• Similarity: 205/401 - (51%)
• Gaps: 44/401 - (10%)

  Fly     8 LLATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTL 72
            |...:||  |..|.::.|.|.|...|:.:|.:|....:|||.:.:.|:|.|:|..||.||.....
Human     4 LSTANVE--FCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDS 66

  Fly    73 VANNYRSL----------------LSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKA 121
            :...::..                .|.:.:.::...|.:|||:|..|......::...:.|.::|
Human    67 LKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQA 131

  Fly   122 KAKSIRLDDPVSAS-AIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQ 185
            :.:::..:.....: ..:|:|:.|:|.|.:.|:......:..:...|||||||||||...|:..:
Human   132 RLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRE 196

  Fly   186 THIADFYVSANEIIPVKMMTLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKE 250
            |..:.|.:|..:.:.|:||....:....::.:...:::||||.|:.|||.|:||..:..|:::::
Human   197 TVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEK 261

  Fly   251 KVGFIDYH-------LEKKSVNVKLPKFKIESKAQLKGIFENLGILDVF-KPSADLNGLVLESGA 307
            ::....:|       :.::.|.|.||:||:|:|.:|..:.::||:.|:| :..|||:|:....|.
Human   262 QLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGL 326

  Fly   308 KIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDNLI--QPPM--EFIADHPFFYVI---HDNK 365
            .:.|.:.|::|.:.|:|.||:||||         |::.  ..||  :|.|:|||.:.|   |.|.
Human   327 YLSKAIHKSYLDVSEEGTEAAAATG---------DSIAVKSLPMRAQFKANHPFLFFIRHTHTNT 382

  Fly   366 VIYFQGHIVEP 376
            :: |.|.:..|
Human   383 IL-FCGKLASP 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	107/387 (28%)
SERPINB11	NP_001357404.1	ovalbumin_like	4..392	CDD:239014	110/399 (28%)
		RCL. /evidence=ECO:0000250	341..365		11/32 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.830