Protein Alignment Spn28B and SERPINB12

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 114/420 - (27%)
• Similarity: 199/420 - (47%)
• Gaps: 65/420 - (15%)

  Fly    17 FWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSE------------- 68
            |..|.::.:...:..:|:.:||:|....:.||.:.:...:..::..||.|:|
Human    23 FCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPDPCL 87

  Fly    69 ----------------NKT----------------LVANNYRSLLSDLKRRETFIILHMANRIYV 101
                            .||                ||:..:..|||.|.|.:|...|.:|||:|.
Human    88 KSNKQKVLADSSLEGQKKTTEPLDQQAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYG 152

  Fly   102 NKKYCLVPEFNQLARKAFKAKAKSIRLD-DPVSASAIVNSWILNRTRGMIRNIVLPKDFNSDTSA 165
            .:::.:..|:.....:.:....:|:... :|..:...:|.|:..:::|.|:.:......|::|..
Human   153 EQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVL 217

  Fly   166 FLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYIDDIDAKIIELPYWNS 230
            .||||:|||.:|...|..:.|..|.|.::|||...|||||.......|:|:::.|:|:|:.|...
Human   218 VLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKAQILEMRYTKG 282

  Fly   231 TLSMRIILP-NSVDGLRKLKEKVGFIDY----------HLEKKSVNVKLPKFKIESKAQLKGIFE 284
            .|||.::|| :|.|.|:.|:|....|.|          ::.::||.:..|:|.:|....|..|.:
Human   283 KLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLEDSYDLNSILQ 347

  Fly   285 NLGILDVF-KPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPP 348
            ::||.|:| :..|||.|:.......:.||:.|.|:::||.|.:|:||||.:...:.     ::..
Human   348 DMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAAAATGAVVSERS-----LRSW 407

  Fly   349 MEFIADHPFFYVIHDNK--VIYFQGHIVEP 376
            :||.|:|||.:.|..||  .|.|.|.:..|
Human   408 VEFNANHPFLFFIRHNKTQTILFYGRVCSP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	113/415 (27%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	113/418 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.980