DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn28B and AT3G45220

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_190108.1	Gene:	AT3G45220 / 823658	AraportID:	AT3G45220	Length:	393	Species:	Arabidopsis thaliana

Alignment Length:	374	Identity:	100/374 - (26%)
Similarity:	173/374 - (46%)	Gaps:	43/374 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 NLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSEN---KTLVANNYRSLLSDLKRRETFIILH 94
            ||::||:|..:::.::...|...|.|::.:.:....:   ..::|......|:|...|..   ||
plant    30 NLVFSPMSINVLLCLIAAGSNCVTKEQILSFIMLPSSDYLNAVLAKTVSVALNDGMERSD---LH 91

  Fly    95 M--ANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRL-DDPVSASAIVNSWILNRTRGMIRNIVLP 156
            :  |..::::|.....|.|..|...::.|....:.. ..|......||:|....|.|:|:.|:..
plant    92 LSTAYGVWIDKSLSFKPSFKDLLENSYNATCNQVDFATKPAEVINEVNAWAEVHTNGLIKEILSD 156

  Fly   157 KDFNS--DTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYIDDID 219
            ....:  ::...|.||:||||.|...|.|..|...||::....::.|..||   :....|::..|
plant   157 DSIKTIRESMLILANAVYFKGAWSKKFDAKLTKSYDFHLLDGTMVKVPFMT---NYKKQYLEYYD 218

  Fly   220 A-KIIELPYWNS--TLSMRIILPNSVDGLRKLKEKVG----FIDYHLEKKSV---NVKLPKFKIE 274
            . |::.|||...  ..:|.|.|||..|||..|.|::.    |:|.|:.::.:   ..|:||||..
plant   219 GFKVLRLPYVEDQRQFAMYIYLPNDRDGLPTLLEEISSKPRFLDNHIPRQRILTEAFKIPKFKFS 283

  Fly   275 SKAQLKGIFENLGILDVF----------KPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASA 329
            .:.:...:.:.:|:...|          .||...|..|.|: ..:..:..||.:::||:|.|| |
plant   284 FEFKASDVLKEMGLTLPFTHGSLTEMVESPSIPENLCVAEN-LFVSNVFHKACIEVDEEGTEA-A 346

  Fly   330 ATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNK--VIYFQGHIVEP 376
            |..|.:..|   |.|:..  :|:|||||.:.:.:.|  ||.|.|.:::|
plant   347 AVSVASMTK---DMLLMG--DFVADHPFLFTVREEKSGVILFMGQVLDP 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	99/369 (27%)
AT3G45220	NP_190108.1	plant_SERPIN	8..390	CDD:238998	99/372 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76659
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
OMA	1	1.010	-	-		QHG57242
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1112
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970