DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28B and Serpine3

DIOPT Version :10

Sequence 1:NP_609128.2 Gene:Spn28B / 34035 FlyBaseID:FBgn0083141 Length:378 Species:Drosophila melanogaster
Sequence 2:XP_063130945.1 Gene:Serpine3 / 691375 RGDID:1585042 Length:410 Species:Rattus norvegicus


Alignment Length:411 Identity:90/411 - (21%)
Similarity:167/411 - (40%) Gaps:83/411 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 LYLLLLATS------VESGFW---EDF----YRILASQNAKRNLIYSPISAEIIMSMVYMASGGK 55
            |:||....|      :..|.|   .:|    |:..|::....|.:.||.|..:.:.::..|:.|.
  Rat     9 LFLLSSCFSAGGGSPLSEGLWLLKTEFALHLYQSAAAETNGTNFVISPASVSLSLEILQFAARGN 73

  Fly    56 TFEELRNVLKFSENKTLVANNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEF-NQLARKAF 119
            |..:|...|.::.....|.....::...|......|.:.:|..:::.....|.|.| .|::|.| 
  Rat    74 TGWQLAEALGYTVQDPRVREFLHTVYITLHNSSQGIGMELACTLFMQTGTSLSPCFVEQVSRWA- 137

  Fly   120 KAKAKSIRLDD---PVSASAIVNSWILNRTRGMIRNIVLPKDFNS------------DTSAFLVN 169
               ..|:.|.|   |       |:..:..::|..|    |.....            .|...:|:
  Rat   138 ---NSSLELADFSEP-------NTTTMEASKGTTR----PSTGEGPGSPLWGRAGALSTQLSIVS 188

  Fly   170 AIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYIDD-----IDAKIIELPYWN 229
            .:.|:..|...|.:.......|..:...::.|..|...|.:..|...|     :|  ::||.|..
  Rat   189 TMTFQSSWQQRFSSVALQPLPFTCAHGLVLQVPAMHQVAEVSYGQFQDAAGHKVD--VLELLYLG 251

  Fly   230 STLSMRIILPNSVDGLRKLKEKVGFIDY---------------HLEKKSVNVKLPKFKIESKAQL 279
            ...|:.::||         ::|...:|:               .|::..::|.||:|:|:::..|
  Rat   252 RVASLLLVLP---------QDKGTPLDHIEPHLTARVIHLWTTRLKRARMDVFLPRFRIQNQFDL 307

  Fly   280 KGIFENLGILDVFKP-SADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDN 343
            |.|..:.||.|:|.| .|:|.|:....|..:.::..||.:::.|:|.::.|||.||..|:.    
  Rat   308 KSILRSWGITDLFDPLKANLKGISGRDGFYVSEVTHKAKMELSEEGTKSCAATAVLLLRRS---- 368

  Fly   344 LIQPPMEFIADHPFFYVIHDN 364
              :.| .|.||.||.:::.::
  Rat   369 --RTP-AFKADRPFIFLLREH 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28BNP_609128.2 serpin42Dd-like_insects 12..376 CDD:381070 87/403 (22%)
Serpine3XP_063130945.1 None

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