Protein Alignment Spn28B and Serpina12

DIOPT Version :10

• Sequence 1: NP_609128.2
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 374
• Identity: 102/374 - (27%)
• Similarity: 171/374 - (45%)
• Gaps: 23/374 - (6%)

  Fly    12 SVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTL-VAN 75
            ::|.||  ...:.|||.:.:.|:..||:|.....||:.:.:...|.||:|....|.|.... |..
Mouse    52 NMEFGF--KLLQRLASNSPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSNWDVHA 114

  Fly    76 NYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNS 140
            .:..||..|.:......:::.|.:::::|......|..||:..:.|........|..:....:|.
Mouse   115 AFHYLLHKLNQETEDTKMNLGNALFMDQKLRPQQRFLNLAKNVYDADMVLTNFQDLENTQKDINR 179

  Fly   141 WILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMT 205
            :|..:|...|:|:|  |..:..|...|.|.|||:|:|.|.|...||...:|::...:.:.|.||.
Mouse   180 YISQKTHSRIKNMV--KSIDPGTVMILTNYIYFRGRWQYEFDPKQTKEEEFFIEKGKTVKVPMMF 242

  Fly   206 LSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKVGFIDYH------LEKKSV 264
            ........|...:...|:|:|| ...::...:||:  :|..||.|:....|..      |.|:.|
Mouse   243 QRGLYDMAYDSQLSCTILEIPY-RGNITATFVLPD--NGKLKLLEQGLQADIFAKWKSLLSKRVV 304

  Fly   265 NVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASA 329
            :|.:||.:|.|...:|.:...|||..:|:.:.||..:......|:.:.|.||.||:||||.|.:|
Mouse   305 DVWVPKLRISSTYNMKKVLSRLGISKIFEENGDLTRISSHRSLKVGEAVHKAELKMDEKGMEGAA 369

  Fly   330 ATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNKV--IYFQGHIVEP 376
            .:|..|..       ::.|.....|.||..:|::|.:  :.|...|.:|
Mouse   370 GSGAQTLP-------METPRHMKLDRPFLMMIYENFMPSMVFLARIYDP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_609128.2	serpin42Dd-like_insects	12..376	CDD:381070	101/372 (27%)
Serpina12	NP_080811.1	serpinA12_vaspin	40..411	CDD:381026	101/372 (27%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		5/24 (21%)