DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28B and Serpinb1a

DIOPT Version :9

Sequence 1:NP_001260209.1 Gene:Spn28B / 34035 FlyBaseID:FBgn0083141 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_079705.2 Gene:Serpinb1a / 66222 MGIID:1913472 Length:379 Species:Mus musculus


Alignment Length:391 Identity:123/391 - (31%)
Similarity:193/391 - (49%) Gaps:41/391 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 TSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVAN 75
            :|..:.|..:.::.|...:...|:.:||.|....::||.:.:.|.|..:|.....|...:. :.:
Mouse     5 SSANTLFALELFQTLNESSPTGNIFFSPFSISSALAMVILGAKGSTAAQLSKTFHFDSVED-IHS 68

  Fly    76 NYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIR-LDDPVSASAIVN 139
            .::||.:::.:|.....|.:|||:|..|.|..:||:....:|.:.|....:. |.....|...:|
Mouse    69 RFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASTQKMYGADLAPVDFLHASEDARKEIN 133

  Fly   140 SWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMM 204
            .|:..:|.|.|..::.....:|.|...|||||||||.|...|..:.|..|.|.:|..:...||||
Mouse   134 QWVKGQTEGKIPELLSVGVVDSMTKLVLVNAIYFKGMWEEKFMTEDTTDAPFRLSKKDTKTVKMM 198

  Fly   205 TLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVD----GLRKL--------------KEK 251
            ........|||.|:..|::|:||....|||.|:||..::    ||:|:              :|.
Mouse   199 YQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPKDIEDESTGLKKIEKQITLEKLLEWTKREN 263

  Fly   252 VGFIDYHLEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPS-ADLNGLVLESGAK---IDKI 312
            :.|||.|       ||||:||||....|......||:.|:|..| |||:|:   ||::   |.||
Mouse   264 LEFIDVH-------VKLPRFKIEESYTLNSNLGRLGVQDLFSSSKADLSGM---SGSRDLFISKI 318

  Fly   313 VQKAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNKV--IYFQGHIVE 375
            |.|:|::::|:|.||:||||.:     :...::.|..||..||||.:.|..|..  :.|.|.:..
Mouse   319 VHKSFVEVNEEGTEAAAATGGI-----ATFCMLLPEEEFTVDHPFIFFIRHNPTSNVLFLGRVCS 378

  Fly   376 P 376
            |
Mouse   379 P 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28BNP_001260209.1 SERPIN 17..373 CDD:238101 121/380 (32%)
Serpinb1aNP_079705.2 serpinB1_LEI 1..379 CDD:381028 122/389 (31%)
CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740 351..379 10/27 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100128
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
98.930

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