Protein Alignment Spn28B and SERPINE3

DIOPT Version :10

• Sequence 1: NP_609128.2
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 86/381 - (22%)
• Similarity: 168/381 - (44%)
• Gaps: 48/381 - (12%)

  Fly    11 TSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVAN 75
            |.:::.|....|:.:|:...:.|.:.||....:.:.::...:.|.|.::|.:.|.::.:...|.:
Human    27 TLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKD 91

  Fly    76 NYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNS 140
            ...::.:.|........:.:|..::|.....|.|.|.:.......:..:...|.:|       ||
Human    92 FLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEP-------NS 149

  Fly   141 WILNRTRGMIRNIV--LPKD------FNSDTSAF----LVNAIYFKGQWLYNFKADQTHIADFYV 193
            ..:..:.|..|...  .|.:      :...::||    ||:.:.|:|.|...|.:..|.|..|..
Human   150 TAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTC 214

  Fly   194 SANEIIPVKMMTLSASLLSGYIDDI---DAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKVGFI 255
            :...::.|.||..:..:..|...|.   ...::||||..|.:|:.::||...|      ..:..|
Human   215 AYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKD------TPLSHI 273

  Fly   256 DYHLEKKSV------------NVKLPKFKIESKAQLKGIFENLGILDVFKP-SADLNGLVLESGA 307
            :.||...::            :|.||:|:|:::..||.|..:.|:.|:|.| .|:|.|:..:.|.
Human   274 EPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGF 338

  Fly   308 KIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHD 363
            .:.:.:.||.:::.|:|.:||.||.:|..::..|      |: |.||.||.|.:.:
Human   339 YVSEAIHKAKIEVLEEGTKASGATALLLLKRSRI------PI-FKADRPFIYFLRE 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_609128.2	serpin42Dd-like_insects	12..376	CDD:381070	85/380 (22%)
SERPINE3	NP_001094790.1	serpinE3	18..400	CDD:381040	86/381 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		7/37 (19%)