Protein Alignment Spn28B and SERPINB4

DIOPT Version :10

• Sequence 1: NP_609128.2
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 116/376 - (30%)
• Similarity: 196/376 - (52%)
• Gaps: 33/376 - (8%)

  Fly    28 QNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKF---SENKTLVANNY------------ 77
            ::.:.|:.|||||....:.||.:.:...|.:::..||.|   :||.|..|..|
Human    21 KSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDRSGNVHHQF 85

  Fly    78 RSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRL-DDPVSASAIVNSW 141
            :.||::..:......|.:||:::..|.|..:.|:....:|.::...:|... :.|..:...:|||
Human    86 QKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEESRKKINSW 150

  Fly   142 ILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTL 206
            :.::|...|:|:.......:||:..|||||||||||...||.:.|....|:.:.|....|:||..
Human   151 VESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQ 215

  Fly   207 SASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKV---GFIDY----HLEKKSV 264
            ..|.....::|:.||::|:||....|||.::|||.:|||:||:||:   ..:::    ::.:..|
Human   216 YNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCV 280

  Fly   265 NVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASA 329
            ::.||:||:|....||.....:|::::|...|||:|:....|..:.|::.|||:::.|:|.||:|
Human   281 DLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAA 345

  Fly   330 ATGVLTRRKKSIDNLIQPPM--EFIADHPFFYVIHDNKV--IYFQGHIVEP 376
            ||.|:      :..|..|..  ||..:|||.:.|..||.  |.|.|....|
Human   346 ATAVV------VVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_609128.2	serpin42Dd-like_insects	12..376	CDD:381070	115/374 (31%)
SERPINB4	NP_002965.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	115/374 (31%)