DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and serpine3

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001116709.1	Gene:	serpine3 / 556612	ZFINID:	ZDB-GENE-050309-223	Length:	417	Species:	Danio rerio

Alignment Length:	406	Identity:	102/406 - (25%)
Similarity:	175/406 - (43%)	Gaps:	51/406 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LATSVESGFWED--------FYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLK 65
            :|.||.|..:.|        .|:.|.....|.|||.||.|..:.:.::.:.:.|.|..:|...|.
Zfish    21 VANSVLSSSFSDLHTQFGISLYQTLTETENKSNLIVSPASVSLCLGLLQLGARGNTLVQLEGTLG 85

  Fly    66 FSENKTLVANNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDD 130
            :..|...|.|.......||......:.|.:||.:::.....|:|||.|.|.........|:...:
Zfish    86 YDVNDVRVQNILSRPQGDLANSSEGLRLQLANALFIQTGVKLLPEFTQHALGWGNTSLLSVNFSN 150

  Fly   131 PVSASAIVNSWI---------------LNRTRGMIRNIVLPKDFNSDTSAF--LVNAIYFKGQWL 178
            |....:.:..|.               |:.:.|......     ..|...:  ||:.:.|.|.|.
Zfish   151 PNHTHSRLQQWAHYQSKADDHLQTREELHHSSGEEEEAT-----RQDHLLYMALVSTLVFHGAWQ 210

  Fly   179 YNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYI---DDIDAKIIELPYWNSTLSMRIILPN 240
            ..|...:|....|..|....:.|.||..|:.:..|:.   .:.:..::||||.:.:|.:.:.||:
Zfish   211 KQFLFTETQNLPFTFSDGSTVKVPMMYQSSEVNIGHFRLPSEQEYTVLELPYLDHSLRLLVALPS 275

  Fly   241 S-VDGLRKLKEK-----VGFIDYHLEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPS-ADL 298
            . ...|.:|:::     ||..|..|.:..:::.||:||::||..||.:.::||:.|:|.|| ||.
Zfish   276 DRKTPLSQLEKQITARAVGLWDTGLRRTKMDIFLPRFKMQSKINLKPVLQSLGVSDIFSPSAADF 340

  Fly   299 NGLVLESGAKIDKIVQKAFLKIDEKGGEASAATG-VLTRRKKSIDNLIQPPMEFIADHPFFYVIH 362
            .|:....|..:.:...:|.:::.|.|.:|::||. ||.:|.:|        ..|.||.||.:::.
Zfish   341 RGISDTDGIFVSEAFHEARIEVTEAGTKAASATAMVLLKRSRS--------AVFKADRPFLFILR 397

  Fly   363 DNKV--IYFQGHIVEP 376
            ....  :.|.|.:|.|
Zfish   398 QISTGSLLFIGRVVNP 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	96/393 (24%)
serpine3	NP_001116709.1	Serpin	35..413	CDD:278507	96/390 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110