Protein Alignment Spn28B and SERPINI2

DIOPT Version :10

• Sequence 1: NP_609128.2
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_006208.1
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 105/397 - (26%)
• Similarity: 202/397 - (50%)
• Gaps: 32/397 - (8%)

  Fly     3 YLYLLLL----------ATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTF 57
            :|:.|||          :....:.|..|.|:.: |.:.|.|:|:||:...:::.||.:.:.||..
Human     5 FLWSLLLLFFGSQASRCSAQKNTEFAVDLYQEV-SLSHKDNIIFSPLGITLVLEMVQLGAKGKAQ 68

  Fly    58 EELRNVLKFSENKT----LVANNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKA 118
            :::|..||..|...    .|..::.|.:|:.|:..||   ::||.:|:.:.:.:..::....::.
Human    69 QQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTF---NLANALYLQEGFTVKEQYLHGNKEF 130

  Fly   119 FKAKAKSIRLDDPVSASAIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKA 183
            |::..|.:...|..:.:.::::|:..:|.|.|:::...::|...|...|||||||||.|...|:.
Human   131 FQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRK 195

  Fly   184 DQTHIADFYVSANEIIPVKMMTLSASLLSGYIDD--IDAKIIELPYWNSTLSMRIILP---NSVD 243
            :.|.:.:|.......:.:.||........||..:  ::.:::||.|.....|:.||||   ..::
Human   196 EDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIE 260

  Fly   244 GLRKLKEKVGFIDY--HLEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESG 306
            .:.||......:.:  .::::.|.:.||:||:|.|...|.:..:|.|.::|....||:|:...|.
Human   261 EVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITDSSE 325

  Fly   307 AKIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDN--KVIYF 369
            ..:.::.||.|.:|:|.|.||:.:||:   ....|.:|.|  .:|||:|||.:::..|  :.|.|
Human   326 VYVSQVTQKVFFEINEDGSEAATSTGI---HIPVIMSLAQ--SQFIANHPFLFIMKHNPTESILF 385

  Fly   370 QGHIVEP 376
            .|.:..|
Human   386 MGRVTNP 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_609128.2	serpin42Dd-like_insects	12..376	CDD:381070	100/376 (27%)
SERPINI2	NP_006208.1	serpinI2_pancpin	23..392	CDD:381042	100/377 (27%)