Protein Alignment Spn28B and SERPINB13

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Alignment Length: 408
• Identity: 113/408 - (27%)
• Similarity: 200/408 - (49%)
• Gaps: 54/408 - (13%)

  Fly    10 ATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVL---------- 64
            |.|...||  |.::.|...| ..|:.:||:.....:.||.:.:.|.|..:|..|.
Human     6 AVSTRLGF--DLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSR 67

  Fly    65 ---------------KFSENKTLVANNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQL 114
                           |..||...|...::..|:::.:......|::.||::..|.|..:.::...
Human    68 IKAEEKEVVRIKAEGKEIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDY 132

  Fly   115 ARKAFKAKAKSIRLDDPVSAS----AIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKG 175
            ..|.:.|..:.:   |.|:|:    ..:|||:.::|...|:::......:|.|...|||.:||||
Human   133 VEKYYHASLEPV---DFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKG 194

  Fly   176 QWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPN 240
            ||...||.:.|....|:::.:....|:|||.|.|....:::|:.|||:.:||.|:.|||.::|||
Human   195 QWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 259

  Fly   241 SVDGLRKLKEKVG---FIDY----HLEKKSVNVKLPKFKIESKAQLKGIFENLGILDVF-KPSAD 297
            .:|||.|:.:|:.   .:::    |:|::.||:.||:|::|....|:.:...:|:.|.| :..||
Human   260 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKAD 324

  Fly   298 LNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPPMEFI-ADHPF-FYV 360
            .:|:...||....|.:..:|:.:.|:|.||:||||:      .......|..|.: .:||| |::
Human   325 YSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGI------GFTVTSAPGHENVHCNHPFLFFI 383

  Fly   361 IHD--NKVIYFQGHIVEP 376
            .|:  |.:::| |....|
Human   384 RHNESNSILFF-GRFSSP 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	109/396 (28%)
SERPINB13	NP_001294852.1	SERPIN	4..400	CDD:294093	112/406 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.980