Protein Alignment Spn28B and SERPINI1

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001116224.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 104/397 - (26%)
• Similarity: 200/397 - (50%)
• Gaps: 29/397 - (7%)

  Fly     4 LYLLLLATSVESG--FWED--------FYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFE 58
            |:.||:..|:.:|  |.|:        .|..|.:.....|:::||:|..:.|.|:.:.:.|.|.:
Human     6 LFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQK 70

  Fly    59 ELRNVLKFSENKTLVANNYRSLLSDL-KRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAK 122
            |:|:.:.:...|.....::....|:: ..:|:..::.:||.::|...:.:..||.|:.:|.|.|.
Human    71 EIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAA 135

  Fly   123 AKSIRLDDPVSASAIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTH 187
            ...:.....|:.:..:|.|:.|.|..:::::|.|:||::.|...|:||:||||.|...|:.:.|.
Human   136 VNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR 200

  Fly   188 IADFYVSANEIIPVKMMTLSASLLSGYIDDID------AKIIELPYWNSTLSMRIILPNSVDGLR 246
            ...|.......:.:.||........|...|..      .:::|:||....:||.::|......|.
Human   201 TFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLA 265

  Fly   247 KLKE--KVGFID---YHLEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESG 306
            .|:.  |...::   ..::|:.|.|.||:|.:|.:..||.:.:.|||.::|...|:|.||.....
Human   266 TLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKE 330

  Fly   307 AKIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNK--VIYF 369
            ..:.|.:.|:||:::|:|.||:|.:|::...:.::   :.|  :.|.|||||::|.:.:  .|.|
Human   331 IFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAV---LYP--QVIVDHPFFFLIRNRRTGTILF 390

  Fly   370 QGHIVEP 376
            .|.::.|
Human   391 MGRVMHP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	98/377 (26%)
SERPINI1	NP_001116224.1	neuroserpin	23..410	CDD:239003	98/380 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930