DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28B and SERPINB9

DIOPT Version :9

Sequence 1:NP_001260209.1 Gene:Spn28B / 34035 FlyBaseID:FBgn0083141 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_004146.1 Gene:SERPINB9 / 5272 HGNCID:8955 Length:376 Species:Homo sapiens


Alignment Length:365 Identity:99/365 - (27%)
Similarity:181/365 - (49%) Gaps:16/365 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 RILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVANNYRSLLSDLKRR 87
            :||...|...|:..||:|....::||.:.:.|.|..::...|..:..:. :...::|||:::.:.
Human    17 KILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEED-IHRAFQSLLTEVNKA 80

  Fly    88 ETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSAS-AIVNSWILNRTRGMIR 151
            .|..:|..|||::..|....:..|.:...:.:.|:.|.:........| ..:|:|:..:|.|.|.
Human    81 GTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIE 145

  Fly   152 NIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYID 216
            .::.....:::|...|||||||||:|...|....|....|.::..|..||:||...|:....::.
Human   146 ELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHVG 210

  Fly   217 DIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKVGFIDYH-------LEKKSVNVKLPKFKIE 274
            ::.|:::||||....||:.::||:....|..:::.:.|....       ::...|.|.|||||::
Human   211 EVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQ 275

  Fly   275 SKAQLKGIFENLGILDVFKP-SADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTRRK 338
            ....::.:..:|||:|.|:. .|||:.:..|....:.|.|.|:|::::|:|.||:||:....   
Human   276 EDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFV--- 337

  Fly   339 KSIDNLIQPPMEFIADHPFFYVIHDNKV--IYFQGHIVEP 376
             ..:..::....|.|||||.:.|..|:.  |.|.|....|
Human   338 -VAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28BNP_001260209.1 SERPIN 17..373 CDD:238101 98/360 (27%)
SERPINB9NP_004146.1 SERPIN 4..376 CDD:320777 98/363 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.930

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