Protein Alignment Spn28B and SERPINB6

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 112/371 - (30%)
• Similarity: 198/371 - (53%)
• Gaps: 28/371 - (7%)

  Fly    23 RILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKT----LVANNYRSLLSD 83
            :.|...|:| |:.:||:|....::||||.:.|.|..::..:|.|  ||:    .:...::|||::
Human    95 KTLGKDNSK-NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF--NKSGGGGDIHQGFQSLLTE 156

  Fly    84 LKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSAS-AIVNSWILNRTR 147
            :.:..|..:|.||||::..|....:..|....:|.::|:.:.:.....|..| ..:|:|:..:|.
Human   157 VNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTE 221

  Fly   148 GMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLS 212
            |.|..::.|...:..|...||||:||:|.|...|..:.|....|.||.||..||:||...::...
Human   222 GKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKK 286

  Fly   213 GYIDDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKV---GFIDY----HLEKKSVNVKLPK 270
            .||.:|..:|:.|||....|:|.|:||:....||.:::::   .|:::    .::::.|.|.||:
Human   287 TYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPR 351

  Fly   271 FKIESKAQLKGIFENLGILDVFK-PSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATG-- 332
            ||:|....::.:..|||:.|.|: ..||.:|: .::...:.|:|.|:|::::|:|.||:|||.
Human   352 FKLEESYDMESVLRNLGMTDAFELGKADFSGM-SQTDLSLSKVVHKSFVEVNEEGTEAAAATAAI 415

  Fly   333 VLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNKV--IYFQGHIVEP 376
            ::.|..:.:.       .|.|||||.:.|..:|.  |.|.|....|
Human   416 MMMRCARFVP-------RFCADHPFLFFIQHSKTNGILFCGRFSSP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	111/366 (30%)
SERPINB6	XP_011512974.1	PAI-2	82..454	CDD:239013	111/369 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.830