Protein Alignment Spn28B and SERPINA1

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 104/366 - (28%)
• Similarity: 182/366 - (49%)
• Gaps: 23/366 - (6%)

  Fly    22 YRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSEN---KTLVANNYRSLLSD 83
            ||.||.|:...|:.:||:|.....:|:.:.:...|.:|:...|.|:..   :..:...::.||..
Human    62 YRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126

  Fly    84 LKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNSWILNRTRG 148
            |.:.::.:.|...|.:::::...||.:|.:..:|.:.::|.::...|...|...:|.::...|:|
Human   127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQG 191

  Fly   149 MIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSG 213
            .|.::|  |:.:.||...|||.|:|||:|...|:...|...||:|.....:.|.||.........
Human   192 KIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQ 254

  Fly   214 YIDDIDAKIIELPYWNSTLSMRIILPNSVDG-LRKLKEKV--GFIDYHLE---KKSVNVKLPKFK 272
            :...:.:.::.:.|..:..:: ..||:  :| |:.|:.::  ..|...||   ::|.::.|||..
Human   255 HCKKLSSWVLLMKYLGNATAI-FFLPD--EGKLQHLENELTHDIITKFLENEDRRSASLHLPKLS 316

  Fly   273 IESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTRR 337
            |.....||.:...|||..||...|||:|:..|:..|:.|.|.||.|.|||||.||:.|..:
Human   317 ITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFL---- 377

  Fly   338 KKSIDNLIQPPMEFIADHPF-FYVIHDN-KVIYFQGHIVEP 376
             ::|...|.|.::|  :.|| |.:|..| |...|.|.:|.|
Human   378 -EAIPMSIPPEVKF--NKPFVFLMIEQNTKSPLFMGKVVNP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	102/361 (28%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	102/361 (28%)
		RCL	368..392		8/30 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010