DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and Spn42Da

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	126/364 - (34%)
Similarity:	204/364 - (56%)	Gaps:	18/364 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKF-SENKTLVANNYRSLLSDLK 85
            |..|:.|....|:::||.|.:...:|..:.:..:|..:|...|.. |.:...:|:::..:|:..:
  Fly    53 YGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAHSFHQVLAAYQ 117

  Fly    86 RRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNSWILNRTRGMI 150
            ..:   ||.:||:|:|...|.|..||:||..|.|.:.|:|:.....|.|:|.:|:|:..||..:|
  Fly   118 DSQ---ILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLI 179

  Fly   151 RNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYI 215
            :::|.....||::...|||||:|||.|.:.|....|....|::.....:.|.||:|........:
  Fly   180 KDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADL 244

  Fly   216 DDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKVGF-----IDYHLEKKSVNVKLPKFKIES 275
            ..:||..:||||.:|.|||.|:|||:..||..|:||:..     |...|.:..|.:|||:||.|.
  Fly   245 PALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEF 309

  Fly   276 KAQLKGIFENLGILDVFKPSADLNGLVLES--GAKIDKIVQKAFLKIDEKGGEASAATGVLTRRK 338
            :.:|..:|:.||:..:|...|:. |.:|:|  ..|:..|:.|||::::|:|.||:||||:..|||
  Fly   310 QVELSEVFQKLGMSRMFSDQAEF-GKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRK 373

  Fly   339 KSIDNLIQP--PMEFIADHPFFYV-IHDNKVIYFQGHIV 374
            ::|   :.|  |:||.|||||.|| :|...:..|.|.:|
  Fly   374 RAI---MSPEEPIEFFADHPFTYVLVHQKDLPLFWGSVV 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	125/361 (35%)
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	125/361 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446376
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm1112
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	10	9.900