Protein Alignment Spn28B and SERPINC1

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 433
• Identity: 106/433 - (24%)
• Similarity: 178/433 - (41%)
• Gaps: 81/433 - (18%)

  Fly    11 TSVESGFWEDFYRILA-SQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFS--ENKT- 71
            :...|.|...||:.|| |:|...|:..||:|.....:|..:.:...|.::|..|.||.  ..||
Human    84 SKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTS 148

  Fly    72 ---------LVANNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIR 127
                     |....||......|       |..|||::.:|.......:..::...:.||.:.:.
Human   149 DQIHFFFAKLNCRLYRKANKSSK-------LVSANRLFGDKSLTFNETYQDISELVYGAKLQPLD 206

  Fly   128 LDDPVSAS-AIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFK----------------- 174
            ..:....| |.:|.|:.|:|.|.|.:::..:..|..|...|||.||||
Human   207 FKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQ 271

  Fly   175 ------------------------GQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYI 215
                                    |.|...|..:.|....||.:..|.....||..........:
Human   272 LTPFFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRV 336

  Fly   216 DDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKV------GFIDYHLEKKSVNVKLPKFKIE 274
            .: ..:::|||:....::|.:|||.....|.|:::::      .::| .||:..:.|.:|:|:||
Human   337 AE-GTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLD-ELEEMMLVVHMPRFRIE 399

  Fly   275 SKAQLKGIFENLGILDVFKP-SADLNGLVLE--SGAKIDKIVQKAFLKIDEKGGEASAATGVLTR 336
            ....||...:::|::|:|.| .:.|.|:|.|  ....:.....||||:::|:|.||:|:|.|:..
Human   400 DGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIA 464

  Fly   337 RKKSIDNLIQPPMEFIADHPFFYVIHD---NKVIYFQGHIVEP 376
            .:....|.:    .|.|:.||...|.:   |.:| |.|.:..|
Human   465 GRSLNPNRV----TFKANRPFLVFIREVPLNTII-FMGRVANP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	104/422 (25%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	106/433 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.940