DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and Spn27A

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001260143.1	Gene:	Spn27A / 45815	FlyBaseID:	FBgn0028990	Length:	447	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	97/376 - (25%)
Similarity:	178/376 - (47%)	Gaps:	27/376 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 WEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGG--KTFEELRNVLKFSENKTLVANNYRSL 80
            |.....:|.::.|.:|:|.||.|.:::::::..|:|.  :|..||.|......::..|...||..
  Fly    78 WHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELANTQTDIRSQNNVREFYRKT 142

  Fly    81 LSDLKR----RETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNSW 141
            |:..|:    .||   |.:..:::.:.......:|....:..:.::.:::...:|.:|:..:|:|
  Fly   143 LNSFKKENQLHET---LSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTNPEAAADAINAW 204

  Fly   142 ILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTL 206
            ..|.|:|.::.:|.|.:..|.. ..|.|.|||.|.|...|..  |....|:.|.::....:.|..
  Fly   205 AANITQGRLQQLVAPDNVRSSV-MLLTNLIYFNGLWRRQFAT--TFQGSFFRSKDDQSRAEFMEQ 266

  Fly   207 SASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDGLRKL-----KEKVGFIDYHLEKKSVNV 266
            :........:.:.|:|:.|||.... |:.::||.:::|:..|     .:::....:.:|:..|.|
  Fly   267 TDYFYYTTSEKLKAQILRLPYKGKN-SLFVLLPYALNGIHDLVKNLENDELKSAQWAMEEVKVKV 330

  Fly   267 KLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLV----LESGAKIDKIVQKAFLKIDEKGGEA 327
            .||||..:.:..||....:||:.::|:.||.|.||.    :....|:..|:|||.:.::|||.||
  Fly   331 TLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRGADVAGKVKVSNILQKAGINVNEKGTEA 395

  Fly   328 SAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNKV--IYFQGHIVEP 376
            .|||.|....|......|:   ||..:.||.:.|.:...  |.|.|.:..|
  Fly   396 YAATVVEIENKFGGSTAIE---EFNVNRPFVFFIEEESTGNILFAGKVHSP 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	96/371 (26%)
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	96/371 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020