DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and Spn100A

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_651818.1	Gene:	Spn100A / 43642	FlyBaseID:	FBgn0039795	Length:	649	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	69/278 - (24%)
Similarity:	128/278 - (46%)	Gaps:	37/278 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 AKSIRLDDPVSASAIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTH 187
            |:|:...|.::::...|| |..|:.|            |.:...|.|.:|::|.|...|...:..
  Fly   371 ARSLFQQDDITSALSANS-ITGRSAG------------SKSKMLLFNGLYYRGSWANPFYQLRDG 422

  Fly   188 IADFYVSANE-IIPVKMMTLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEK 251
            ..:|:...|| .:...||..........:..:.|:::.|||..|..::.|:||:..:||..:..:
  Fly   423 SDEFFFMTNEDAVKAPMMHARGKFQVADLPQVKARVLSLPYETSRYALCIVLPDETEGLSDVISQ 487

  Fly   252 VGFIDYHLEK-----KSVNVKLPKFKIESKAQLKGIFENLGILDVF-KPSADLNGLVLESGAKID 310
            :...|:.|.|     |.:::.:|||::|..::.:.:.:.:|:..|| :..|.|:.|..:....:|
  Fly   488 LQTSDFLLAKKQFQMKELHISMPKFQVEETSRSEAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVD 552

  Fly   311 KIVQKAFLKIDEKGGEA---SAATGVLTRRKKSIDNLIQPPME----------FIADHPFFYVIH 362
            :|||...:::||.|..|   ||||  :..|..|:::.:.|..|          |..:.||.|.|.
  Fly   553 EIVQFVNVRVDEGGSSANSLSAAT--MQARTPSVESTVLPVPEPEPELPGVERFEVNRPFAYFIV 615

  Fly   363 D--NKVIYFQGHIVEPRW 378
            |  .:.:...|.|..|.:
  Fly   616 DCQEQFVLASGKIYTPEF 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	67/271 (25%)
Spn100A	NP_651818.1	SERPIN	41..>148	CDD:294093
Spn100A	NP_651818.1	SERPIN	<380..628	CDD:294093	64/262 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010