DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and Spn85F

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_649965.2	Gene:	Spn85F / 41221	FlyBaseID:	FBgn0037772	Length:	640	Species:	Drosophila melanogaster

Alignment Length:	238	Identity:	56/238 - (23%)
Similarity:	96/238 - (40%)	Gaps:	34/238 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 LPKDFNSDTSAFLVNAIYFKGQWLYNFKADQ-THIADFYVSANEIIPVKMMTLSASLLSGYIDDI 218
            :|..|...|:.|..:.|....:...|:..|. :|:  ||:...:::.......:|.|...|.:.:
  Fly   415 VPAAFAPITNDFEPHYIGEAAEGKSNYNTDVISHV--FYLGNQQVVHTTFKVYNAVLYYKYFEHL 477

  Fly   219 DAKIIELPYWNSTLSMRIILPN------SVDGLRKLKEKVGFIDYHLEKKSVNVKLPKFKIESKA 277
            ...::||.......::.|:||:      :.....||...:..:...|:.:.|...:|.||:....
  Fly   478 KMSVLELELDTPEYNLMILLPDYHTDIVAAAASLKLGPTLRLMRKQLKPRWVQAIIPDFKLHGTM 542

  Fly   278 QLKGIFENLGILDVFKPS-ADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSI 341
            .|....:|:||.|||:|: ||...:..|.|..:..|.|    .||            :|.|...|
  Fly   543 FLTNDLQNMGICDVFEPNRADFRPMTEEKGVYVRHIEQ----SID------------VTIRTHPI 591

  Fly   342 DNLIQ------PPMEFIADHP--FFYVIHDNKVIYFQGHIVEP 376
            :.|.:      .|::...:||  ||.|..|..|....|.|:.|
  Fly   592 NQLKRNYGAQSKPIQISVNHPFLFFIVDRDLDVAVMSGRILNP 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	54/233 (23%)
Spn85F	NP_649965.2	SERPIN	88..>204	CDD:294093
Spn85F	NP_649965.2	SERPIN	<450..634	CDD:294093	47/199 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010