DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and SERPINA9

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_783866.3	Gene:	SERPINA9 / 327657	HGNCID:	15995	Length:	417	Species:	Homo sapiens

Alignment Length:	388	Identity:	90/388 - (23%)
Similarity:	171/388 - (44%)	Gaps:	42/388 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKT---LV 73
            |:.:.|....||.|..:...:|:.:||:|....::|:.:.:...|..::...|.|:...|   .:
Human    46 SLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAI 110

  Fly    74 ANNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIV 138
            ...::.|:..|......:.|.|.:.::|.|:..|...|....::.::|:..|....:|..|.|.:
Human   111 HQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARI 175

  Fly   139 NSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTH-IADFYVSANEIIPVK 202
            ||.:..:|:|.:.:|:...|..  |:..|||.|:||.:|...|..:.|. ...|.|.....:.|.
Human   176 NSHVKKKTQGKVVDIIQGLDLL--TAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVP 238

  Fly   203 MMTLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKVGF-----IDYHLEKK 262
            ||........|...:::..::::.|....::. .:|| |...:|:|::.:..     ..:.|:|:
Human   239 MMHQKEQFAFGVDTELNCFVLQMDYKGDAVAF-FVLP-SKGKMRQLEQALSARTLRKWSHSLQKR 301

  Fly   263 SVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEA 327
            .:.|.:|:|.|.:...|:.|...:||.:||..:||.:|:......::.|...||.|.:.|:|.||
Human   302 WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEA 366

  Fly   328 SAATGV--LTRRKKSIDNLIQPPMEFIADHPFFYVIHDNKV------------IYFQGHIVEP 376
            :|||..  :.|.|               |.|.::.:..|:.            |.|.|.:..|
Human   367 TAATTTKFIVRSK---------------DGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	88/378 (23%)
SERPINA9	NP_783866.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020