DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and Spn28Db

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster

Alignment Length:	385	Identity:	128/385 - (33%)
Similarity:	204/385 - (52%)	Gaps:	33/385 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKYLYLLLLATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLK 65
            :|||.|||:||||...|..:... |....|:.|.|.||:..||.:||:.|.:.|.|.||||:||.
  Fly     7 IKYLVLLLIATSVLGKFKLNLLE-LVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLD 70

  Fly    66 FSENKTLVANNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDD 130
            ...:.|.:|..|..::|:.::...   |...|.:|||:.|.:..::|.|.:..|.|:.|     |
  Fly    71 LPVDVTEMAKKYERIMSNFQKHNG---LRFTNWLYVNETYEVRQDYNTLMKSTFMAEGK-----D 127

  Fly   131 PVS---ASAIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFY 192
            |:|   ||..::..|..::...:|.|....:...:.||.|||.:|:.|.|...|....|.:..|:
  Fly   128 PLSQRKASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFH 192

  Fly   193 VSANEIIPVKMMTLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILP------NSVDG-LRKLKE 250
            ...|:.:.|:||:.....  ...|....:|||:|:.||.|||.|.||      :|::. ||.|.|
  Fly   193 GDHNKKVYVRMMSHVGRF--RIADHSYGQIIEMPFDNSDLSMIIGLPLHNTYLSSIEKILRTLSE 255

  Fly   251 KVGFIDYHLEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLE-SGAKIDKIVQ 314
            .       |.:.:|:|:||||||:.:.:|....:.|||..:|..::||:||:.. :||||:.:|.
  Fly   256 S-------LVENNVHVELPKFKIKYQTELVESLKKLGIHLIFSNTSDLSGLLTNGTGAKINHVVH 313

  Fly   315 KAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNKVIYFQGHIV 374
            |:|::|:|:|    |:||..:...:||....:....|..:.||.::|.|...:||:|.:|
  Fly   314 KSFIEINERG----ASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRDKHTVYFRGRVV 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	117/366 (32%)
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	117/367 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468704
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H76659
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900