DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and Serpinb6a

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_006253933.1	Gene:	Serpinb6a / 291085	RGDID:	735108	Length:	400	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	117/366 - (31%)
Similarity:	197/366 - (53%)	Gaps:	22/366 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVL---KFSEN-KTLVANNYRSLLSDLKRR 87
            |:::..|:..||||....::||:|.:.|.|..::...|   |.|.| ...|...::|||:::.:.
  Rat    41 SEDSSNNIFLSPISISAALTMVFMGAKGMTASQMVQTLSLDKCSGNGGGDVHQGFQSLLAEVNKT 105

  Fly    88 ETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRL-DDPVSASAIVNSWILNRTRGMIR 151
            .|..:|..|||::..|...::..|....||.::|:.:.:.. .|...:...:|:|:..:|...|:
  Rat   106 GTQYLLKTANRLFGEKTCDILASFKDACRKFYEAEMEELDFKGDTEQSRQRINTWVAKKTEDKIK 170

  Fly   152 NIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYID 216
            .::.|...:.||...|||||||||.|...|..:.|....|.||..|..||:||.:.::....||.
  Rat   171 ELLAPGIVDPDTVLVLVNAIYFKGNWDKQFNKEHTREKPFKVSKTEEKPVQMMFMKSTFKMTYIG 235

  Fly   217 DIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKV---GFIDY----HLEKKSVNVKLPKFKIE 274
            :|..||:.|||..:.|:|.|:||:....|:.:::::   .||::    .|:::.|.|.||:||:|
  Rat   236 EIFTKILLLPYAGNELNMIIMLPDEHIELKTVEKELTYEKFIEWTRLDMLDEEEVEVFLPRFKLE 300

  Fly   275 SKAQLKGIFENLGILDVF-KPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATG-VLTRR 337
            ....:|.:...||:.|.| :..||.:|:..:.|..:.|::.|||::::|:|.||.|||| .:|.|
  Rat   301 ENYDMKVVLGKLGMTDAFMEGRADFSGIASKQGLFLSKVIHKAFVEVNEEGTEAVAATGSTITMR 365

  Fly   338 KKSIDNLIQPPMEFIADHPF-FYVIH-DNKVIYFQGHIVEP 376
                  .::....|:||||| |::.| ..|.|.|.|....|
  Rat   366 ------CLRFTPRFLADHPFLFFIQHVKTKGILFCGRFSSP 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	116/361 (32%)
Serpinb6a	XP_006253933.1	SERPIN	25..400	CDD:294093	116/364 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830