DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and Serpinf1

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_808788.1	Gene:	Serpinf1 / 287526	RGDID:	631369	Length:	418	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	88/383 - (22%)
Similarity:	173/383 - (45%)	Gaps:	36/383 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFS-ENKTL 72
            ||.:| |.|..|.||:.:...:..|::.||:|....:|.:.:.:..:|...:...|.:. .|...
  Rat    54 LAAAV-SNFGYDLYRLRSGAVSTGNILLSPLSVATALSALSLGAEQRTESVIHRALYYDLINNPD 117

  Fly    73 VANNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAI 137
            :.:.|:.||:.:...|.  ....|:||...:|..:...|.....|::..:.: |...:|......
  Rat   118 IHSTYKELLASVTAPEK--NFKSASRIVFERKLRVKSSFVAPLEKSYGTRPR-ILTGNPRIDLQE 179

  Fly   138 VNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVK 202
            :|:|:..:.:|.|....  ::..|..|..|:...||||||...|.:.:|.:.||::..:..:.|.
  Rat   180 INNWVQAQMKGKIARST--REMPSALSILLLGVAYFKGQWATKFDSRKTTLQDFHLDEDRTVRVP 242

  Fly   203 MMTLSASLLS-GYIDDIDAKIIELPYWNSTLSMRIILPNSV-DGLRKLKEK-----VGFIDYHLE 260
            ||:...::|. |...|::.||.:||...| :|:...||.:| ..|..::|.     |..||..|:
  Rat   243 MMSDPKAILRYGLDSDLNCKIAQLPLTGS-MSIIFFLPLTVTQNLTMIEESLTSEFVHDIDRELK 306

  Fly   261 KKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAFLKIDEKGG 325
            .....:.:||.|:..:..:....:::.:..:|: |.|.: .:.....|:.::..:|..:.:|:|.
  Rat   307 TIQAVLTVPKLKLSYEGDVTNSLQDMKLQSLFE-SPDFS-KITGKPVKLTQVEHRAAFEWNEEGA 369

  Fly   326 EASAATGVLTRRKKSIDNLIQP-----PMEFIADHPFFYVIHDNK--VIYFQGHIVEP 376
            ..|:...            :||     |:::..:.||.:|:.|..  .:.|.|.|::|
  Rat   370 GTSSNPD------------LQPVRLTFPLDYHLNRPFIFVLRDTDTGALLFIGRILDP 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	82/370 (22%)
Serpinf1	NP_808788.1	PEDF	40..415	CDD:239007	87/381 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100