DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28B and Serpinb1b

DIOPT Version :9

Sequence 1:NP_001260209.1 Gene:Spn28B / 34035 FlyBaseID:FBgn0083141 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_766640.1 Gene:Serpinb1b / 282663 MGIID:2445361 Length:382 Species:Mus musculus


Alignment Length:389 Identity:120/389 - (30%)
Similarity:193/389 - (49%) Gaps:34/389 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 TSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVAN 75
            :|..:.|..:.:..|...:...|:.:||.|....::||::.:.|.|..:|...|.|...:. :.:
Mouse     5 SSANTLFTLELFHTLKESSPTGNIFFSPFSISSSLAMVFLGAKGSTAAQLSKTLHFDSVED-IHS 68

  Fly    76 NYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDD-PVSASAIVN 139
            .::||.:::.:......|.:|||:|..|.|..:|||....:|.:.|...::.... ...|...:|
Mouse    69 CFQSLTAEVSKLGASHTLKLANRLYGEKTYNFLPEFLASTQKMYSADLAAVDFQHASEDARKEIN 133

  Fly   140 SWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMM 204
            .|:..:|.|.|..::.....:|.|...|||||||||.|...|...:|..|.|.::..:...||||
Mouse   134 QWVKGQTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPFRLNKKDTKTVKMM 198

  Fly   205 TLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVD----GLRKLKEKVGFIDYH------- 258
            ........|||.|:..|::|:||....|||.|:||..::    ||:|::|::.....|       
Mouse   199 YQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLKKIEEQLTLGKLHEWTKHEN 263

  Fly   259 LEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKP-SADLNGLVLESGAK---IDKIVQKAFLK 319
            |....|:||||:||:|....|......||:.|:|.. .|||:|:   ||::   :.|||.|:|:.
Mouse   264 LRNIDVHVKLPRFKMEESYILNSNLCCLGVQDLFSSGKADLSGM---SGSRDLFVSKIVHKSFVD 325

  Fly   320 IDEKGGEASAATG----VLTRRKKSIDNLIQPPMEFIADHPFFYVIHDN---KVIYFQGHIVEP 376
            ::|:|.||:||||    ||..:..:      |...|..||||.:.|..|   .:|:| |.:..|
Mouse   326 VNEQGTEAAAATGGIIQVLCEKMPT------PQEVFTVDHPFLFFIRHNPTANMIFF-GRVCSP 382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28BNP_001260209.1 SERPIN 17..373 CDD:238101 118/378 (31%)
Serpinb1bNP_766640.1 serpinB1_LEI 1..382 CDD:381028 119/387 (31%)
CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740 352..382 10/30 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100128
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
98.930

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