Protein Alignment Spn28B and SERPINA11

DIOPT Version :10

• Sequence 1: NP_609128.2
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 95/376 - (25%)
• Similarity: 179/376 - (47%)
• Gaps: 39/376 - (10%)

  Fly    22 YRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVAN---NYRSLLSD 83
            |:.||: :|..|:.:||:|....::::.:.:...|...:...|.|:..:|..|:   .:||||..
Human    62 YKELAA-DAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHT 125

  Fly    84 LKRRETFIILHMANRIYVNKKYCLVPEFNQL--ARKAFKAKAKSIRLDDPVSASAIVNSWILNRT 146
            |......:.|.:.|.::::|:  |.|..:.|  .::.:.|.|.|....|.|:....:|.::..:|
Human   126 LALPSPKLELKVGNSLFLDKR--LKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQT 188

  Fly   147 RGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIAD-FYVSANEIIPVKMMTLSASL 210
            .|.:.: .|| :|:.||...|.|.|:||.:|.:.|...||...: |:|.....:.|.||......
Human   189 YGQVVD-CLP-EFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMH 251

  Fly   211 LSGYIDDIDAKIIELPYWNSTLSMRIILPN-----SVDG------LRKLKEKV--GFIDYHLEKK 262
            ...|..|:...::::.|..:.|:: ::||:     .|:.      |||..:.:  ..:|.|
Human   252 RFLYDQDLACTVLQIEYRGNALAL-LVLPDPGKMKQVEAALQPQTLRKWGQLLLPSLLDLH---- 311

  Fly   263 SVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEA 327
                 ||:|.|.....|:.|...:|:.::....||.:|:..:....|.|:..||.:.:.|||.||
Human   312 -----LPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEA 371

  Fly   328 SAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHD--NKVIYFQGHIVEP 376
            .||:|:|: :..|::.:..|...|  :.||..::.:  .:.:.|.|.:|.|
Human   372 GAASGLLS-QPPSLNTMSDPHAHF--NRPFLLLLWEVTTQSLLFLGKVVNP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_609128.2	serpin42Dd-like_insects	12..376	CDD:381070	94/374 (25%)
SERPINA11	NP_001073920.1	serpinA11	50..422	CDD:381025	95/376 (25%)