Protein Alignment Spn28B and SERPINA11

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 95/376 - (25%)
• Similarity: 179/376 - (47%)
• Gaps: 39/376 - (10%)

  Fly    22 YRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVAN---NYRSLLSD 83
            |:.||: :|..|:.:||:|....::::.:.:...|...:...|.|:..:|..|:   .:||||..
Human    62 YKELAA-DAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHT 125

  Fly    84 LKRRETFIILHMANRIYVNKKYCLVPEFNQL--ARKAFKAKAKSIRLDDPVSASAIVNSWILNRT 146
            |......:.|.:.|.::::|:  |.|..:.|  .::.:.|.|.|....|.|:....:|.::..:|
Human   126 LALPSPKLELKVGNSLFLDKR--LKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQT 188

  Fly   147 RGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIAD-FYVSANEIIPVKMMTLSASL 210
            .|.:.: .|| :|:.||...|.|.|:||.:|.:.|...||...: |:|.....:.|.||......
Human   189 YGQVVD-CLP-EFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMH 251

  Fly   211 LSGYIDDIDAKIIELPYWNSTLSMRIILPN-----SVDG------LRKLKEKV--GFIDYHLEKK 262
            ...|..|:...::::.|..:.|:: ::||:     .|:.      |||..:.:  ..:|.|
Human   252 RFLYDQDLACTVLQIEYRGNALAL-LVLPDPGKMKQVEAALQPQTLRKWGQLLLPSLLDLH---- 311

  Fly   263 SVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEA 327
                 ||:|.|.....|:.|...:|:.::....||.:|:..:....|.|:..||.:.:.|||.||
Human   312 -----LPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEA 371

  Fly   328 SAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHD--NKVIYFQGHIVEP 376
            .||:|:|: :..|::.:..|...|  :.||..::.:  .:.:.|.|.:|.|
Human   372 GAASGLLS-QPPSLNTMSDPHAHF--NRPFLLLLWEVTTQSLLFLGKVVNP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	93/371 (25%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	93/371 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010