Protein Alignment Spn28B and Serpina1

DIOPT Version :10

• Sequence 1: NP_609128.2
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001421270.1
• Gene: Serpina1 / 24648
• RGDID: 3326
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 372
• Identity: 103/372 - (27%)
• Similarity: 188/372 - (50%)
• Gaps: 27/372 - (7%)

  Fly    20 DF----YRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVANNYRS- 79
            ||    ||.|..|:...|:.:||:|.....:|:.:.|.|.|.:::...|:|:..:...|:.:::
  Rat    50 DFAFSLYRELVHQSNTSNIFFSPMSITTAFAMLSLGSKGDTRKQILEGLEFNLTQIPEADIHKAF 114

  Fly    80 --LLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNSWI 142
              ||..|.|.::.:.|:..|.::|||...||.:|.:..:..:.::|.|:...|...|..::|.::
  Rat   115 HHLLQTLNRPDSELQLNTGNGLFVNKNLKLVEKFLEEVKNNYHSEAFSVNFADSEEAKKVINDYV 179

  Fly   143 LNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLS 207
            ...|:|.|  :.|.|..:.||...|||.|:|||:|...|..:.|..|||:|..:..:.|.||...
  Rat   180 EKGTQGKI--VDLMKQLDEDTVFALVNYIFFKGKWKRPFNPEHTRDADFHVDKSTTVKVPMMNRL 242

  Fly   208 ASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDGLRK------LKEKVGFIDYHLEKKSVNV 266
            ......|...:.:.::.:.|..:..:: .:||:  ||..:      .|:.:.....:.:.:|..:
  Rat   243 GMFDMHYCSTLSSWVLMMDYLGNATAI-FLLPD--DGKMQHLEQTLTKDLISRFLLNRQTRSAIL 304

  Fly   267 KLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAAT 331
            ..||..|.....||.:..:|||..||...|||:|:..::..|:.:.|.||.|.:||:|.||:.||
  Rat   305 YFPKLSISGTYNLKTLLSSLGITRVFNNDADLSGITEDAPLKLSQAVHKAVLTLDERGTEAAGAT 369

  Fly   332 GVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNKV--IYFQGHIVEP 376
            .|     :::...:.|.::|  ||||.::|.:::.  ..|.|.:::|
  Rat   370 VV-----EAVPMSLPPQVKF--DHPFIFMIVESETQSPLFVGKVIDP 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_609128.2	serpin42Dd-like_insects	12..376	CDD:381070	102/370 (28%)
Serpina1	NP_001421270.1	serpinA1_A1AT	44..411	CDD:381012	103/372 (28%)
		RCL	367..386		5/25 (20%)