DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and Serpine1

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_036752.2	Gene:	Serpine1 / 24617	RGDID:	3249	Length:	402	Species:	Rattus norvegicus

Alignment Length:	378	Identity:	104/378 - (27%)
Similarity:	175/378 - (46%)	Gaps:	27/378 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVANNYRS 79
            :.|....::.:...:..||:::||.....:::|:.:.:.|||.:::::.:.|:.::...|...|.
  Rat    36 TNFGVKVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERGTAPALRK 100

  Fly    80 LLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNSWILN 144
            |..:|........:..|:.|:|.:...||..|.....|.|:...|.:...:...|..|:|.|:..
  Rat   101 LSKELMGSWNKNEISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQVDFSEMERARFIINDWVER 165

  Fly   145 RTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSAS 209
            .|:|||.:::.....|..|...||||:||.|||...|....||...|:.|....|.|.||..:..
  Rat   166 HTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDGSTISVPMMAQNNK 230

  Fly   210 LLSGYI-----DDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKVGFIDYHL--EKKSVNVK 267
            .  .|.     |..:..|:||||...||||.|..|...|  ..|......:|..|  :.||...:
  Rat   231 F--NYTEFTTPDGHEYDILELPYHGETLSMFIAAPFEKD--VPLSAITNILDAELIRQWKSNMTR 291

  Fly   268 ------LPKFKIESKAQLKGIFENLGILDVFKPS-ADLNGLVLESGAKIDKIVQKAFLKIDEKGG 325
                  ||||.:|::..|:|..|.||:.|:|..: ||...|..:....:.:.:||..::::|.|.
  Rat   292 LPRLLILPKFSLETEVDLRGPLEKLGMTDIFSSTQADFTSLSDQEQLSVAQALQKVKIEVNESGT 356

  Fly   326 EASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDN--KVIYFQGHIVEP 376
            .||::|.:|...:.:       |.|.:.|..|.:|:..|  :.|.|.|.::||
  Rat   357 VASSSTAILVSARMA-------PTEMVLDRSFLFVVRHNPTETILFMGQLMEP 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	102/371 (27%)
Serpine1	NP_036752.2	serpin	29..402	CDD:422956	102/376 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020