DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn28B and Serpina3j

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001094942.1	Gene:	Serpina3j / 238395	MGIID:	2182843	Length:	420	Species:	Mus musculus

Alignment Length:	394	Identity:	107/394 - (27%)
Similarity:	181/394 - (45%)	Gaps:	46/394 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTL 72
            |...|:.:.|....|:.||.:|..:|.::||:|..|.::.:.:.:.|.|.||:...|||:..:|.
Mouse    45 LTLASINTDFAFSLYKKLALKNPHKNFVFSPLSITIALASLSLGAKGNTLEEILEGLKFNLTETP 109

  Fly    73 VAN---NYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSA 134
            .|:   .:..||..|.:....:.:...|.:.|.|...::.||.:.||..:..:..:.....|..|
Mouse   110 EADIHQGFGHLLQRLSQPGDQVQISTGNSMVVEKHLQILAEFKEKARALYHTEVFTADFQQPREA 174

  Fly   135 SAIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEII 199
            ..::|.::.|:|:|||:.:|  .|....||..:.|...|.|:|...|...:|.:..|.......:
Mouse   175 RKLLNDYVSNQTQGMIKELV--SDLEERTSMVMTNFALFNGKWNMTFDPYETFMGTFIEDRRTPV 237

  Fly   200 PVKMMTLSASLLSGYIDDIDAK--IIELPYWNSTLSMRIILPNSVDGLRKLKEKVGFIDYHLE-- 260
            .|.||.:. .|.:.|..|...|  ::||.|..:..:| .|||:.    .|:|:    ::..|:
Mouse   238 KVSMMKMK-ELRAPYFRDEKMKCTVVELNYKGNGKAM-FILPDQ----GKMKQ----VEASLQPA 292

  Fly   261 -----KKSVNVK------LPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQ 314
                 :||:..:      ||||.|....:|:.|...|||.:||...|||:|:......::.::..
Mouse   293 TLRGWRKSLRPRMIDELYLPKFSISKNYRLENILPELGIKEVFSTQADLSGISGGKDVRVSRMFH 357

  Fly   315 KAFLKIDEKGGEASAATG-----VLTRRKKSIDNLIQPPMEFIADHPF-FYVIH-DNKVIYFQGH 372
            .|.|.:.|.|.||.|.|.     :.|:...::.||         :.|| |.|:| |::.|.|.|.
Mouse   358 SAALDMTETGTEARATTRDKYDFLSTKSNPTVVNL---------NTPFLFCVLHSDSENIDFMGK 413

  Fly   373 IVEP 376
            |..|
Mouse   414 INNP 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	103/380 (27%)
Serpina3j	NP_001094942.1	serpinA3_A1AC	37..417	CDD:381019	106/392 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100