DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28B and Serpinb8

DIOPT Version :9

Sequence 1:NP_001260209.1 Gene:Spn28B / 34035 FlyBaseID:FBgn0083141 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_035589.1 Gene:Serpinb8 / 20725 MGIID:894657 Length:374 Species:Mus musculus


Alignment Length:365 Identity:102/365 - (27%)
Similarity:181/365 - (49%) Gaps:18/365 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 RILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVANNYRSLLSDLKRR 87
            :||:.::..|||.:.|:|....::|||:.:.|.|..::..||..|.|.. |..::::||:::.:.
Mouse    17 KILSEKDKSRNLFFCPMSVSSALAMVYLGAKGNTATQMSEVLGLSGNGD-VHQSFQTLLAEINKT 80

  Fly    88 ETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRL-DDPVSASAIVNSWILNRTRGMIR 151
            :|..:|..|.|::..:....:..|.:...|.::|..:.:.. .|.......:|.|:..:|.|.|.
Mouse    81 DTQYLLKSACRLFGEESCDFLSTFKESCHKFYQAGLEELSFAKDTEGCRKHINDWVSEKTEGKIS 145

  Fly   152 NIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYID 216
            .::.|......|...||||:||||:|...|....|....|..: .|...|:||...|....|::|
Mouse   146 EVLSPGTVCPLTKLVLVNAMYFKGKWKAQFDRKYTRGMPFKTN-QEKKTVQMMFKHAKFKMGHVD 209

  Fly   217 DIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKVGFIDYH-------LEKKSVNVKLPKFKIE 274
            :::.:::.|||....|||.|:||:....|..:::.:.:....       |.:..|.|.||:.|:|
Mouse   210 EVNMQVLALPYAEEELSMVILLPDESTDLAVVEKALTYEKLRAWTNPETLTESQVQVFLPRLKLE 274

  Fly   275 SKAQLKGIFENLGILDVFKPS-ADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTRRK 338
            ....|:.:.:|||:.|.|:.: ||.:|:..:....:.|:..|.|::::|:|.||:|||.|:...:
Mouse   275 ESYDLETVLQNLGMTDAFEETRADFSGMTTKKNVPVSKVAHKCFVEVNEEGTEAAAATAVIRNAR 339

  Fly   339 KSIDNLIQPPMEFIADHPFFYVI--HDNKVIYFQGHIVEP 376
                 ..:....|.|||||.:.|  |....|.|.|....|
Mouse   340 -----CCRTEPRFCADHPFLFFIWHHKTSSILFCGRFSSP 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28BNP_001260209.1 SERPIN 17..373 CDD:238101 101/360 (28%)
Serpinb8NP_035589.1 SERPIN 4..374 CDD:294093 101/363 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.930

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