DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28B and Serpina1d

DIOPT Version :9

Sequence 1:NP_001260209.1 Gene:Spn28B / 34035 FlyBaseID:FBgn0083141 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_033272.1 Gene:Serpina1d / 20703 MGIID:891968 Length:413 Species:Mus musculus


Alignment Length:375 Identity:114/375 - (30%)
Similarity:186/375 - (49%) Gaps:32/375 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 DF----YRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVANNYRS- 79
            ||    ||.|..|:...|:.:||:|.....:|:.:.|.|.|..::...|:|:..:|..|:.::| 
Mouse    50 DFALRLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHKSF 114

  Fly    80 --LLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSASAIVNSWI 142
              ||..|.|.::.:.|...|.::||....||.:|.:.|:..::|:..|:...:...|..::|.::
Mouse   115 QHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFV 179

  Fly   143 LNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLS 207
            ...|:|.|...|  |..:.||...|.|.|.|||:|...|..:.|..|:|:|..:..:.|.|||||
Mouse   180 EKGTQGKIVEAV--KKLDQDTVFALANYILFKGKWKQPFDPENTEEAEFHVDESTTVKVPMMTLS 242

  Fly   208 ASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDG-LRKL-----KEKVGFIDYHLEKKSVNV 266
            ..|...:...:.:.::.:.|..:|.:: .:||:  || ::.|     ||.:.....:..:....:
Mouse   243 GMLDVHHCSMLSSWVLLMDYAGNTTAV-FLLPD--DGKMQHLEQTLNKELISQFLLNRRRSDAQI 304

  Fly   267 KLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESG-AKIDKIVQKAFLKIDEKGGEASAA 330
            .:|:..|.....||.:...|||..:|...|||:|:..|:. .|:.|.|.||.|.|||.|.||:||
Mouse   305 HIPRLSISGNYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSKAVHKAVLTIDETGTEAAAA 369

  Fly   331 TGVLTRRKKSIDNLIQPP-MEFIADHPFFYVI---HDNKVIYFQGHIVEP 376
            | ||     .:.....|| :.|  ||||.::|   |....| |.|.:|:|
Mouse   370 T-VL-----QVATYSMPPIVRF--DHPFLFIIFEEHTQSPI-FVGKVVDP 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28BNP_001260209.1 SERPIN 17..373 CDD:238101 112/370 (30%)
Serpina1dNP_033272.1 SERPIN 53..410 CDD:214513 111/370 (30%)
RCL 368..387 8/26 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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