DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28B and Serpina1a

DIOPT Version :9

Sequence 1:NP_001260209.1 Gene:Spn28B / 34035 FlyBaseID:FBgn0083141 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_001239498.1 Gene:Serpina1a / 20700 MGIID:891971 Length:436 Species:Mus musculus


Alignment Length:381 Identity:111/381 - (29%)
Similarity:190/381 - (49%) Gaps:27/381 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 LATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLV 73
            :||:: ..|....||.|..|:...|:.:||:|.....:|:.:.|.|.|..::...|:|:..:|..
Mouse    67 IATNL-GDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSE 130

  Fly    74 ANNYRS---LLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSAS 135
            |:.::|   ||..|.|.::.:.|...|.::||....||.:|.:.|:..::|:..|:...:...|.
Mouse   131 ADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAK 195

  Fly   136 AIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIP 200
            .::|.::...|:|.|...|  |..:.||...|.|.|.|||:|...|..:.|..|:|:|..:..:.
Mouse   196 KVINDFVEKGTQGKIAEAV--KKLDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDESTTVK 258

  Fly   201 VKMMTLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDG-LRKL-----KEKVGFIDYHL 259
            |.|||||..|...:...:.:.::.:.|..:..:: .:||:  || ::.|     ||.:.....:.
Mouse   259 VPMMTLSGMLHVHHCSTLSSWVLLMDYAGNATAV-FLLPD--DGKMQHLEQTLSKELISKFLLNR 320

  Fly   260 EKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESG-AKIDKIVQKAFLKIDEK 323
            .::...:..|:..|..:..||.:...|||..:|...|||:|:..|:. .|:.:.|.||.|.|||.
Mouse   321 RRRLAQIHFPRLSISGEYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKAVLTIDET 385

  Fly   324 GGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVI---HDNKVIYFQGHIVEP 376
            |.||:|.| ||    :.:...:.|.:.|  ||||.::|   |....| |.|.:|:|
Mouse   386 GTEAAAVT-VL----QMVPMSMPPILRF--DHPFLFIIFEEHTQSPI-FLGKVVDP 433

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28BNP_001260209.1 SERPIN 17..373 CDD:238101 107/368 (29%)
Serpina1aNP_001239498.1 SERPIN 76..433 CDD:214513 107/369 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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