Protein Alignment Spn28B and Serpina1a

DIOPT Version :10

• Sequence 1: NP_609128.2
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001239498.1
• Gene: Serpina1a / 20700
• MGIID: 891971
• Length: 436
• Species: Mus musculus
• Alignment Length: 381
• Identity: 111/381 - (29%)
• Similarity: 190/381 - (49%)
• Gaps: 27/381 - (7%)

  Fly     9 LATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLV 73
            :||:: ..|....||.|..|:...|:.:||:|.....:|:.:.|.|.|..::...|:|:..:|..
Mouse    67 IATNL-GDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSE 130

  Fly    74 ANNYRS---LLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSAS 135
            |:.::|   ||..|.|.::.:.|...|.::||....||.:|.:.|:..::|:..|:...:...|.
Mouse   131 ADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAK 195

  Fly   136 AIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIP 200
            .::|.::...|:|.|...|  |..:.||...|.|.|.|||:|...|..:.|..|:|:|..:..:.
Mouse   196 KVINDFVEKGTQGKIAEAV--KKLDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDESTTVK 258

  Fly   201 VKMMTLSASLLSGYIDDIDAKIIELPYWNSTLSMRIILPNSVDG-LRKL-----KEKVGFIDYHL 259
            |.|||||..|...:...:.:.::.:.|..:..:: .:||:  || ::.|     ||.:.....:.
Mouse   259 VPMMTLSGMLHVHHCSTLSSWVLLMDYAGNATAV-FLLPD--DGKMQHLEQTLSKELISKFLLNR 320

  Fly   260 EKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESG-AKIDKIVQKAFLKIDEK 323
            .::...:..|:..|..:..||.:...|||..:|...|||:|:..|:. .|:.:.|.||.|.|||.
Mouse   321 RRRLAQIHFPRLSISGEYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKAVLTIDET 385

  Fly   324 GGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVI---HDNKVIYFQGHIVEP 376
            |.||:|.| ||    :.:...:.|.:.|  ||||.::|   |....| |.|.:|:|
Mouse   386 GTEAAAVT-VL----QMVPMSMPPILRF--DHPFLFIIFEEHTQSPI-FLGKVVDP 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_609128.2	serpin42Dd-like_insects	12..376	CDD:381070	108/376 (29%)
Serpina1a	NP_001239498.1	serpinA1_A1AT	67..435	CDD:381012	111/381 (29%)