Protein Alignment Spn28B and SERPINA3

DIOPT Version :9

• Sequence 1: NP_001260209.1
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001076.2
• Gene: SERPINA3 / 12
• HGNCID: 16
• Length: 423
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 103/387 - (26%)
• Similarity: 187/387 - (48%)
• Gaps: 31/387 - (8%)

  Fly     8 LLATSVESGFWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTL 72
            |.:.:|:..|  ..|:.|..:...:|:|:||:|....::.:.:.:...|..|:...|||:..:|.
Human    49 LASANVDFAF--SLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETS 111

  Fly    73 VA---NNYRSLLSDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRLDDPVSA 134
            .|   .:::.||..|.:....:.|.|.|.::|.::..|:..|.:.|::.:.::|.:....|..:|
Human   112 EAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAA 176

  Fly   135 SAIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEII 199
            ..::|.::.|.|||.|.:::  ||.:|.|...|||.|:||.:|...|....||.:.||:|..:.:
Human   177 KKLINDYVKNGTRGKITDLI--KDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWV 239

  Fly   200 PVKMMTLSASLLSGYID-DIDAKIIELPYWNSTLSMRIILPNS-----------VDGLRKLKEKV 252
            .|.||:|....:..:.| ::...::||.| ....|...|||:.           .:.|::.::.:
Human   240 MVPMMSLHHLTIPYFRDEELSCTVVELKY-TGNASALFILPDQDKMEEVEAMLLPETLKRWRDSL 303

  Fly   253 GFIDYHLEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADLNGLVLESGAKIDKIVQKAF 317
            .|      ::...:.||||.|.....|..|...|||.:.|...|||:|:.......:.::|.||.
Human   304 EF------REIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAV 362

  Fly   318 LKIDEKGGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVI--HDNKVIYFQGHIVEPR 377
            |.:.|:|.||||||.|   :...:..|::.......:.||..:|  .|.:.|:|...:..|:
Human   363 LDVFEEGTEASAATAV---KITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPK 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	100/372 (27%)
SERPINA3	NP_001076.2	serpinA3_A1AC	40..421	CDD:381019	102/385 (26%)
		RCL	369..394		9/27 (33%)
		O-glycosylated at one site	381..389		1/7 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010