DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and serpinb10

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_031760330.1	Gene:	serpinb10 / 100497689	XenbaseID:	XB-GENE-5769609	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	105/372 - (28%)
Similarity:	182/372 - (48%)	Gaps:	19/372 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FWEDFYRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVANNYRSLL 81
            |..|..|.::...|.:|:::|.:|..|.::|||:.:.|.|..::...|.|.|.:.:.| .:|.||
Frog    10 FTIDVLREISKTAAGQNVVFSSMSIMISLAMVYLGAHGNTAADMGKALHFDEVEDVHA-QFRVLL 73

  Fly    82 SDLKRRETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRL-DDPVSASAIVNSWILNR 145
            .:|.:......|...|:::..|||..:|.|.:.....:.|..:.:.. .:|.:..:.:|:||..:
Frog    74 KELMKNGNDYTLTTVNKLFGEKKYYFLPTFLKAINAFYGAPLEKVDFSSNPEATRSYINAWIQEK 138

  Fly   146 TRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSANEIIPVKMMTLSASL 210
            |:|.|:|::.....:.:|...:.|.:||...|...|....|..|.|.:..||.|.|.||....:.
Frog   139 TKGKIQNLLPENSISPNTVLMVANTLYFLANWTTQFSEHATSKAPFTLITNEQIKVNMMATMNTF 203

  Fly   211 LSGYIDDIDAKIIELPYWNS-TLSMRIILPNSVDGLRKLKEKVGFIDYHLEKKSVN-------VK 267
            ....|.:....::||||.:: .|||.|:||::...|.|:..::.:.:.....:|.|       |.
Frog   204 NMKRIKNPGMSVLELPYGDTKDLSMVIMLPDNSTVLTKVDREISYENLSKWTRSENMSSNYLAVY 268

  Fly   268 LPKFKIESKAQLKGIFENLGILDVFKPS-ADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAAT 331
            ||:|::|....||.:..:||:...|..| |:.:|:..:....:..:..|.|::::|||.||::||
Frog   269 LPRFRMEKSFSLKKVLSSLGMSSAFSQSRANFSGMGKQKQLYVSDVHHKTFIEVNEKGTEAASAT 333

  Fly   332 GVLTRRKKSIDNLIQPPMEFIADHPFFYVIHDNKV--IYFQGHIVEP 376
            |.:    .||.:|...  ||.||.||.:.|..||.  |...|....|
Frog   334 GSV----MSIRSLANE--EFKADRPFHFFIRHNKTNCILLYGKFYSP 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	104/367 (28%)
serpinb10	XP_031760330.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010