DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28B and serpini1

DIOPT Version :9

Sequence 1:	NP_001260209.1	Gene:	Spn28B / 34035	FlyBaseID:	FBgn0083141	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_031757359.1	Gene:	serpini1 / 100144746	XenbaseID:	XB-GENE-948443	Length:	428	Species:	Xenopus tropicalis

Alignment Length:	405	Identity:	120/405 - (29%)
Similarity:	198/405 - (48%)	Gaps:	37/405 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKYLYLLLL--------ATSVESGFWEDF----YRILASQNAKRNLIYSPISAEIIMSMVYMASG 53
            |.:|.||.|        .|||......:|    |..|.:.....|:|:||:|..|.:.||.:.:.
Frog    19 MHHLSLLALIVMQALVFGTSVHDETVNEFSIKVYHKLRATIEDENIIFSPLSTAIALGMVELGAR 83

  Fly    54 GKTFEELRNVLKFSENKTLVANNYRSLLSDLKR----RETFIILHMANRIYVNKKYCLVPEFNQL 114
            |.:.:|:|:||.:.:.|.   ....|||.||..    :|...:|.:||.:|:...:.:..:|.||
Frog    84 GSSLKEIRHVLGYDKLKN---GEEFSLLKDLSNMLTAQEKHYVLSIANSLYLQNGFHISDKFIQL 145

  Fly   115 ARKAFKAKAKSIRLDDPVSASAIVNSWILNRTRGMIRNIVLPKDFNSDTSAFLVNAIYFKGQWLY 179
            .:|.|||:.:::......:.:..:|.|:.|.|...||::|...||.:.|...||||:||||.|..
Frog   146 MKKYFKAEVENVDFSQGSTVANHINMWVENHTNNRIRDLVTADDFTNLTKLVLVNAMYFKGNWKS 210

  Fly   180 NFKADQTHIADFYVSANEIIPVKMMTLSASLLSGYIDDID------AKIIELPYWNSTLSMRIIL 238
            .|:.:.|....|.......:.:.||........|...|..      .:::||||....:|:.|:|
Frog   211 QFRPENTRTFSFTKDDESEVQIPMMYQKGEFYYGEFTDGSNEAGGVYQVLELPYEGDEISLIIVL 275

  Fly   239 PNSVDGLRKLKE--KVGFID---YHLEKKSVNVKLPKFKIESKAQLKGIFENLGILDVFKPSADL 298
            ......|..|:.  |...|:   ..::|:.|.|.||:||:|....||.:...|||..:|...|||
Frog   276 SRQEVPLATLEPLLKAPLIEEWANSVKKQKVEVYLPRFKVEEVVNLKDVLMQLGITKIFSGEADL 340

  Fly   299 NGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTRRKKSIDNLIQPPMEFIADHPFFYVIHD 363
            :.:.......:.|.|.|:||:::|:|.||:|::|::...:.::   :.|  :.|.|||||:||.:
Frog   341 SAVSDSKDLFVAKAVHKSFLEVNEEGSEAAASSGMIANSRMAV---LYP--QVIVDHPFFFVIRN 400

  Fly   364 NKV--IYFQGHIVEP 376
            .|.  :.|.|.::.|
Frog   401 RKTGSVLFMGRVMHP 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28B	NP_001260209.1	SERPIN	17..373	CDD:238101	111/376 (30%)
serpini1	XP_031757359.1	serpinI1_NSP	41..412	CDD:381005	111/378 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010