Protein Alignment RapGAP1 and ralgapa2

DIOPT Version :9

• Sequence 1: NP_001097114.2
• Gene: RapGAP1 / 34032
• FlyBaseID: FBgn0264895
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: XP_001920508.2
• Gene: ralgapa2 / 568210
• ZFINID: ZDB-GENE-131122-56
• Length: 2015
• Species: Danio rerio
• Alignment Length: 646
• Identity: 148/646 - (22%)
• Similarity: 237/646 - (36%)
• Gaps: 142/646 - (21%)

  Fly   183 SEERVPQPHSPHDSHAHPHNGGLQHSGSRATLRH--SMNHSSSSTVSGSACSSTPASPQLSGVVS 245
            |.|.:|.......:|...|.|....||..|.|..  |.||.:....|....|....||.|...|
Zfish  1446 SMELIPLTARMVMTHLVNHLGHHPLSGGPALLNSLISENHDNPYVESSELSSEVFKSPNLQLFV- 1509

  Fly   246 ASGCQLLSNGHHYQSQSSVSSNSSIVSAIPASQRLLEEALAKPAPYPMILLPLHGGY-W------ 303
            .:...|:|    |....|.:||::.:||.|...         .:...:|:..:.|.| |
Zfish  1510 FNDSTLIS----YLQIPSDNSNTAPLSANPRDH---------SSEVRIIIRDISGKYSWDSGVLF 1561

  Fly   304 --MDGT-----------EHECG-YDARGNPLLPQTTWMAKFETDDTAKCYRRFYAAREHSNLIGL 354
              :|||           .||.. .:.|.:....:.:  ::.:.:|......:......||:...|
Zfish  1562 RTLDGTGVTSSDSREQSSHEAARLEKRSSVRFSKCS--SELDVEDGVDVLDQLLEDLGHSSPECL 1624

  Fly   355 DE-QL-------GPILLSIKTENV--------ANQEHMRILMR------LRTGTMHELLPVSCLL 397
            .| ||       .|:.::::.|.:        :.||...::.|      :|.....|  |..
Zfish  1625 PEPQLRLTQPPSPPMGMNLEIEGLIMEAVHRQSKQEEEELMRRQIEDPSVRAERQKE--PTH--- 1684

  Fly   398 PQP-SPAKMAHTLNENITVE--------HFMPILCPKASQL---ISVYDEHVLVSHFKFGVLYQR 450
            .:| ||..:...|..::.:.        |    |..|.|:|   :...|........|..|.|..
Zfish  1685 QEPKSPFYLCRLLLNDLGMNSWDRRKSFH----LLKKNSKLLRELKNLDSRQCRETHKIAVFYIG 1745

  Fly   451 YGQTTEEELFGNQQTSPAFDEFLDVLGQRIRLKDHKGYRGGLDIQNGHTGDTAVYEVFKEREIMF 515
            .||..:..:..|.|.|..:::|:..||..:.|..|.|:.|||. :||.||.||.|......|::|
Zfish  1746 EGQEDKYSILSNTQGSQVYEDFVSGLGWEVNLATHCGFMGGLQ-RNGSTGSTAPYYATSNVEVIF 1809

  Fly   516 HVSTLLPHTEGDPQQLQRKRHIGNDIVAIVFQETNTPFSPDMIASHFLHAFIVVQPIEPNTPHTR 580
            ||||.:| ::.|....::.||:|||.|.||:.|....:...:|.:.|....:::.|::    :..
Zfish  1810 HVSTRMP-SDSDDSITKKLRHLGNDEVHIVWSEHTRDYRRGIIPTDFGDVLVIIYPMK----NHM 1869

  Fly   581 YKVSVTARDDVPFFGPTLPNPAVFRKGQEFKEFILTKLINAENACYKAEKFAKLEQRTRTSLLQN 645
            :.|.:..:..||||||......|  .|:.....:....|||..|.           ::|..|.|:
Zfish  1870 FFVQIMKKPQVPFFGPLFDGAIV--TGELLPSLVRATCINASRAV-----------KSRLPLYQS 1921

  Fly   646 LCEE--------LREKTRDFLGTDLSQTSAGSPTPETPKAESGSGGNAGSRFIDTVKKALIMRVR 702
            ..||        ::....:....|.: ....||:|     .....|.|||....|
Zfish  1922 FYEERALYLEAIIQNHKENMTFEDFA-AQVFSPSP-----SYWPSGGAGSLSCST---------- 1970

  Fly   703 SQSVDTGNGHGPGQTDKFSVNTKLGTLNSKKETHPEMQTPNLNTCSRTASKSSSK-SKSSN 762
              |.|              ::..:.|.:|..:..|.:.....|..|....:|:|. |||||
Zfish  1971 --SAD--------------LSVSVMTNDSGDQVSPTIPRATKNRVSGKLRRSASAISKSSN 2015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RapGAP1	NP_001097114.2	GoLoco	147..168	CDD:280368
		Rap_GAP	460..639	CDD:280332	52/178 (29%)
ralgapa2	XP_001920508.2	Rap_GAP	1755..1927	CDD:280332	57/190 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3686
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810