Protein Alignment RapGAP1 and LOC4577025

DIOPT Version :10

• Sequence 1: NP_001097114.2
• Gene: RapGAP1 / 34032
• FlyBaseID: FBgn0264895
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: XP_061503738.1
• Gene: LOC4577025 / 4577025
• VectorBaseID: AGAMI1_004203
• Length: 1304
• Species: Anopheles gambiae
• Alignment Length: 689
• Identity: 182/689 - (26%)
• Similarity: 282/689 - (40%)
• Gaps: 186/689 - (26%)

  Fly    19 SEISLAPSSAASSPKPLHRMIKYWRNSSGKIPGLRKS-----ESFAEYR--RHSSNSATISGGSG 76
            |.:.|.||.:::||           :|:|:    |||     |||.|.:  |....|...|...|
Mosquito    11 SGLLLEPSPSSASP-----------SSAGR----RKSVALRAESFDEQQLLRVQQPSRPASSTPG 60

  Fly    77 GRSSTSSARQLQYQRLEMESCENIDMLTEPLRRQHAFMANTQKQQPAGGGSGSGSVTHSPERLRG 141
            ...|:|:.|.....:..........:|.....:   |:.:.:.....|..|.|.:|...|....|
Mosquito    61 CSLSSSNVRPQSSPKFFRTQSFGDRLLASASPK---FVKSKKMFHSIGPKSSSSTVLFYPPETAG 122

  Fly   142 ATTATQDLFELLERVQCSRLDDQRCVLPAYFSQNHHRGSNASEERVPQPHSPHDSHAHPHNGGLQ 206
            :.                         ||.........||......|..|.|..::
Mosquito   123 SP-------------------------PAGAGSARQPESNGRTREPPAGHDPLGAY--------- 153

  Fly   207 HSGSRATLRHSMN------HSSSSTVSGSACSSTPASPQLSGVVSASGCQLLS-----NGHHYQS 260
                |..||....      .|.||::|....:.:...|      |.|..:|:|     :..||.|
Mosquito   154 ----REELRQLRQLQKERFRSRSSSISIERWNESATGP------STSATELISRRGVFSRRHYGS 208

  Fly   261 QSSVSSNSSIVSAIPASQRLLEEALAKPAPYPMILLPLHGGYWMDGTEHECGY------------ 313
                      |..:|.|:                         :||.:..|..
Mosquito   209 ----------VDQLPQSE-------------------------IDGLDPNCRRFRLENGESLAEK 238

  Fly   314 -DARGNPLLP-------QTTWMAKFETDDTAKCYRRFYAAREHSNLIGLDEQLGPILLSIKTENV 370
             :..|:|.:|       ||.|            |.:::..:.|.|.:|:|.:..|..|||.:::.
Mosquito   239 DEVFGSPSIPILENPEHQTRW------------YFKYFLGKLHQNYVGMDSEKSPYFLSIVSQDS 291

  Fly   371 ANQ--EHMRILMRLRTGTMHELLPVSCLLPQPSPAKMAHTLNENITVEHFMPIL-------CPKA 426
            .::  ...|:::..:.|.....||.:   ||           :.:||:..:...       .||.
Mosquito   292 GSKCMPLYRVMLFRKQGAQKLALPYN---PQ-----------QKLTVKQILSNFTLMDSNKSPKE 342

  Fly   427 SQLISVYDEHVLVS------HFKFGVLYQRYGQTTEEELFGNQQTSPAFDEFLDVLGQRIRLKDH 485
            .....:..:.:|:.      :|||||:|.:.||..::|:..|:..||.||:||.:||::|||||.
Mosquito   343 IFAADIQKDLLLLEEQEGSVNFKFGVVYMKAGQKLDDEMLSNETGSPEFDDFLTLLGEKIRLKDW 407

  Fly   486 KGYRGGLDIQNGHTGDTAVYEVFKEREIMFHVSTLLPHTEGDPQQLQRKRHIGNDIVAIVFQE-- 548
            :.||||||::...||..::|.:::..|||||||||||.:..:.||::||||||||||.|:|.:
Mosquito   408 ERYRGGLDVKGDMTGKYSIYTLYEGHEIMFHVSTLLPFSRDNRQQVERKRHIGNDIVNIIFIDEA 472

  Fly   549 ---TNTPFSPDMIASHFLHAFIVVQPIEPNTPHTRYKVSVTARDDVPFFGPTLPNPAVFRKGQEF 610
               ..|.|.|:.:.|.|.|.|.||     ....|||:::|...:.||.||||||||..|.....|
Mosquito   473 SSGEETEFIPNNVKSQFTHVFAVV-----TKRGTRYRLAVYCDETVPPFGPTLPNPPEFEDPAVF 532

  Fly   611 KEFILTKLINAENACYKAEKFAKLEQRTRTSLLQNLCEE 649
            ::|:|.||||.|.|.::...||:..:||...|:::|.||
Mosquito   533 RDFLLVKLINGEKATFQTPTFARKRERTLEMLIKDLYEE 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RapGAP1	NP_001097114.2	GoLoco	147..168	CDD:460481	0/20 (0%)
		Rap_GAP	460..639	CDD:460463	84/183 (46%)
LOC4577025	XP_061503738.1	None