Protein Alignment RapGAP1 and Ralgapa2

DIOPT Version :9

• Sequence 1: NP_001097114.2
• Gene: RapGAP1 / 34032
• FlyBaseID: FBgn0264895
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: XP_038962548.1
• Gene: Ralgapa2 / 296211
• RGDID: 1308023
• Length: 1988
• Species: Rattus norvegicus
• Alignment Length: 657
• Identity: 149/657 - (22%)
• Similarity: 223/657 - (33%)
• Gaps: 204/657 - (31%)

  Fly   141 GATTATQDLFELLERVQCSRLD--------DQRCVLPAYFSQNHHRGS---------NASEERVP 188
            |::|.||.....|.....|..|        :.|...|..:..:...|:         ..|.|.:|
  Rat  1408 GSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPVQYHSSADLGNLLTVEEEKKRRSVELIP 1472

  Fly   189 QPHSPHDSHAHPHNGGLQHSGSRATLRHSM---NHSSSSTVSGSACSSTPASPQLSGVVSASGCQ 250
            .......:|...|.|....||..|.| ||:   ||.::........|....||.|
  Rat  1473 LTARMVMAHLVNHLGHYPLSGGPAVL-HSLVSENHDNAHVEGTELSSEVFRSPNL---------- 1526

  Fly   251 LLSNGHHYQSQSSVSSNSSIVSAIPASQRLLEEALAKPAPYP-------------MILLPLHGGY 302
                      |..|.::|:::|           .|..||..|             :|:..:.|.|
  Rat  1527 ----------QLFVFNDSTLIS-----------YLQTPAEGPAGGTSGGSLSDVRVIVRDISGKY 1570

  Fly   303 WMDGT-------------------------EHECGYDARGNPLLPQTTWMAKFETDDTAKCYRRF 342
            ..||.                         .|.||         ||:......|.||.
  Rat  1571 SWDGKVLYGPLEGRLAPSGRNPSFQISGWHHHTCG---------PQSNLFHGEEGDDV------- 1619

  Fly   343 YAAREHSNLIGLDEQLG--------PILLSIK----TENVAN--QEHMRILMRLRTGTMHELLPV 393
                    |..|.|.:|        |..|::.    |.:..|  ||...|.:.||..|..:....
  Rat  1620 --------LDKLLENIGHTSPECLLPSQLNLNEPSPTPSAMNCDQEKEIIEVILRQSTQEDEYVQ 1676

  Fly   394 SC---------LLPQPSPA------------------------KMAHTLNENITVEHFMPILCPK 425
            .|         ...||||.                        |..|.|.:|           .|
  Rat  1677 RCHSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKN-----------SK 1730

  Fly   426 ASQLISVYDEHVLVSHFKFGVLYQRYGQTTEEELFGNQQTSPAFDEFLDVLGQRIRLKDHKGYRG 490
            ..:.:...|........|..|.|...||..:..:..|::.|.|:::|:..||..:.|..|.|:.|
  Rat  1731 LLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMG 1795

  Fly   491 GLDIQNGHTGDTAVYEVFKEREIMFHVSTLLPHTEGDPQQLQRKRHIGNDIVAIVFQETNTPFSP 555
            ||. :||.||.||.|......|::|||||.:| ::.|....::.||:|||.|.||:.|.:..:..
  Rat  1796 GLQ-RNGSTGQTAPYYATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRR 1858

  Fly   556 DMIASHFLHAFIVVQPIEPNTPHTRYKVSVTARDDVPFFGPTLPNPAVFRKGQEFKEFILTKLIN 620
            .:|.:.|....|::.|::    :..:.:::|.:.:||||||......|  .|:.....|....||
  Rat  1859 GIIPTAFGDVSIIIYPMK----NHMFFITITKKPEVPFFGPLFDGAIV--SGKLLPSLICATCIN 1917

  Fly   621 AENA--C-------YKAEKFAKLEQRTRTSLLQNLCEELREKTRDFLGTDLSQTSAGSPTPETPK 676
            |..|  |       :..|:...||     :::||..|.:  ...||      .....||:|.  .
  Rat  1918 ASRAVKCLIPLYQSFYEERALYLE-----AIIQNHREVM--TFEDF------AAQVFSPSPS--Y 1967

  Fly   677 AESGSGG 683
            :.||:||
  Rat  1968 SLSGTGG 1974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RapGAP1	NP_001097114.2	GoLoco	147..168	CDD:280368	5/28 (18%)
		Rap_GAP	460..639	CDD:280332	58/187 (31%)
Ralgapa2	XP_038962548.1	Rap_GAP	1765..1937	CDD:396632	56/179 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910