Protein Alignment RapGAP1 and Ralgapa2

DIOPT Version :9

• Sequence 1: NP_001097114.2
• Gene: RapGAP1 / 34032
• FlyBaseID: FBgn0264895
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: XP_006499580.1
• Gene: Ralgapa2 / 241694
• MGIID: 3036245
• Length: 1966
• Species: Mus musculus
• Alignment Length: 619
• Identity: 136/619 - (21%)
• Similarity: 206/619 - (33%)
• Gaps: 194/619 - (31%)

  Fly   141 GATTATQDLFELLERVQCSRLD--------DQRCVLPAYFSQNHHRGS---------NASEERVP 188
            |::|.||.....|.....|..|        :.|...|..:..:...|:         ..|.|.:|
Mouse  1392 GSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPIQYHSSADLGNLLTVEEEKKRRSVELIP 1456

  Fly   189 QPHSPHDSHAHPHNGGLQHSGSRATLRHSM---NHSSSSTVSGSACSSTPASPQLSGVVSASGCQ 250
            .......:|...|.|....||..|.| ||:   ||.::........|....||.|
Mouse  1457 LTARMVMAHLVNHLGHYPLSGGPAVL-HSLVSENHDNAHVEGTELSSEVFRSPNL---------- 1510

  Fly   251 LLSNGHHYQSQSSVSSNSSIVSAIPASQRLLEEALAKPAPYP-------------MILLPLHGGY 302
                      |..|.::|:::|           .|..||..|             :|:..:.|.|
Mouse  1511 ----------QLFVFNDSTLIS-----------YLQTPAEGPAGGTSGGSLSDVRVIVRDISGKY 1554

  Fly   303 WMDGT-------------------------EHECGYDARGNPLLPQTTWMAKFETDDTAKCYRRF 342
            ..||.                         .|.||         ||.......|.||.
Mouse  1555 SWDGKVLYGPLEGRLAPNGRNPSFQISGWHHHTCG---------PQKDLFNGEEGDDV------- 1603

  Fly   343 YAAREHSNLIGLDEQLG--------PILLSIK----TENVANQEHMRILMR--LRTGTMHELLPV 393
                    |..|.|.:|        |..|::.    |....|.:..:.:|.  ||.....:....
Mouse  1604 --------LDKLLENIGHTSPECLLPSQLNLNEPSPTPCAMNWDQEKAIMEVILRQSAQEDEYVQ 1660

  Fly   394 SC---------LLPQPSPA------------------------KMAHTLNENITVEHFMPILCPK 425
            .|         ...||||.                        |..|.|.:|           .|
Mouse  1661 RCNSDSSVTVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKN-----------SK 1714

  Fly   426 ASQLISVYDEHVLVSHFKFGVLYQRYGQTTEEELFGNQQTSPAFDEFLDVLGQRIRLKDHKGYRG 490
            ..:.:...|........|..|.|...||..:..:..|::.|.|:::|:..||..:.|..|.|:.|
Mouse  1715 LLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMG 1779

  Fly   491 GLDIQNGHTGDTAVYEVFKEREIMFHVSTLLPHTEGDPQQLQRKRHIGNDIVAIVFQETNTPFSP 555
            ||. :||.||.||.|......|::|||||.:| ::.|....::.||:|||.|.||:.|.:..:..
Mouse  1780 GLQ-RNGSTGQTAPYYATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRR 1842

  Fly   556 DMIASHFLHAFIVVQPIEPNTPHTRYKVSVTARDDVPFFGPTLPNPAVFRKGQEFKEFILTKLIN 620
            .:|.:.|....|::.|::    :..:.:::|.:.:||||||......|  .|:.....|....||
Mouse  1843 GIIPTAFGDVSIIIYPMK----NHMFFITITKKPEVPFFGPLFDGAIV--SGKLLPSLICATCIN 1901

  Fly   621 AENA--C-------YKAEKFAKLEQRTRTSLLQN 645
            |..|  |       :..|:...||     :::||
Mouse  1902 ASRAVKCLIPLYQSFYEERALYLE-----AIIQN 1930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RapGAP1	NP_001097114.2	GoLoco	147..168	CDD:280368	5/28 (18%)
		Rap_GAP	460..639	CDD:280332	58/187 (31%)
Ralgapa2	XP_006499580.1	Rap_GAP	1749..1921	CDD:366939	56/179 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3686
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810