Protein Alignment RapGAP1 and LOC1273968

DIOPT Version :10

• Sequence 1: NP_001097114.2
• Gene: RapGAP1 / 34032
• FlyBaseID: FBgn0264895
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: XP_061497090.1
• Gene: LOC1273968 / 1273968
• VectorBaseID: AGAMI1_006025
• Length: 2252
• Species: Anopheles gambiae
• Alignment Length: 948
• Identity: 191/948 - (20%)
• Similarity: 317/948 - (33%)
• Gaps: 303/948 - (31%)

  Fly     5 RTLVDH-----GH-PIIVGSSEISLAPS------SAASSPKPLHRMIKYWRNSSGKIPG---LRK 54
            :|:..|     || |:.:|::.:|....      ||..:..|:|..:      ||..|.   |::
Mosquito  1474 KTVAMHLITNLGHFPMGIGATRLSSLVDEQDDLMSATGAAAPVHPGV------SGAAPSVAMLQR 1532

  Fly    55 SESFA-------EYRRHSSN------------------SATISGGSGGRSSTSSARQ--LQYQRL 92
            ..|.|       |:...|.|                  :..:.||.......::.||  |..:.|
Mosquito  1533 ENSIAGARVDAMEHVLASPNLQLLMLSPELVASFIELPALKLPGGGATAGLLTANRQVRLLLRDL 1597

  Fly    93 EMESCENIDMLTE---------------------PLRRQHAFMANTQKQQPAGGG--SGSGSVTH 134
            ..::|.:..:|.:                     |:.|.:||..     .|.|.|  :|:||||
Mosquito  1598 NGKACWDASILYQEPALSAGSNDTDRNATFQSAAPVSRHYAFAT-----VPTGSGQLAGAGSVT- 1656

  Fly   135 SPERLRGATTATQDLFELLERVQCSRLDDQRCVLPAYFSQNHHRGSNASEE-------RVPQPHS 192
                                                   ..|....:||.:       .:|..|.
Mosquito  1657 ---------------------------------------ARHFASGSASIDPLMSTAIGLPMSHG 1682

  Fly   193 PHDSHAHPHNGGLQHSGSRATLRHSMNHSSSSTVSGSACSSTPASPQLSGVVSASGCQLLSNGHH 257
            |                 |.||||...|...     .|....|...||..::...|
Mosquito  1683 P-----------------RHTLRHRPVHQLP-----VAKDLAPDLDQLDDLLQYIG--------- 1716

  Fly   258 YQS-----QSSVSSNSSIVSAIPA-----------SQRLLE-EALAKPAPYPMILLPLHGGYWMD 305
            |.|     .|.|..|::..|.:.|           :||.:| ||:|:...
Mosquito  1717 YTSPECLDSSEVPLNTAGPSPLGAALEGQTISIILNQRTIEAEAVARQNA--------------- 1766

  Fly   306 GTEHECGYDARGNPLLPQTTWMAKFETDDTAKCYRRFYAAREHSNLIGLDEQLGPILLSIKTENV 370
            ||..:.|.|..    ||..|  :.:.|..::..|..:...:.:|:    |...|.|..:..|  :
Mosquito  1767 GTTGQPGVDRS----LPSGT--SSYPTLVSSSGYGSYSPGQSYSD----DSGTGTIARAANT--M 1819

  Fly   371 ANQEHMRILMRLRTGTMHELLPVSCLLPQPSPAKMAHTLNENITV--------EHFMPILCPKAS 427
            ..|:..:.|.|....|              .|.::...|...:.:        .|.:........
Mosquito  1820 QTQQQQQQLDRSDATT--------------KPFQLGRILFNQLGLAGWERRKRTHLLQRTDKLLR 1870

  Fly   428 QLISVYDEHVLVSHFKFGVLYQRYGQTTEEELFGNQQTSPAFDEFLDVLGQRIRLKDHKGYRGGL 492
            :|.::.::....:| |..|:|...||..:..:..|...|..::.|:..||..:.|:.|.|:.|||
Mosquito  1871 ELRNLDNQKCRETH-KMAVIYVANGQEDKGSILRNACGSSTYEMFVSALGWEVELESHNGFLGGL 1934

  Fly   493 DIQNGHTGDTAVYEVFKEREIMFHVSTLLPHTEGDPQQ-LQRKRHIGNDIVAIVFQETNTPFSPD 556
            ..|.  .|.||.|......|:::||||.:|  ...|:. |.:.||:|||.|.||:.|.|..:..|
Mosquito  1935 PRQG--CGQTAPYYATPFLEVIYHVSTRMP--SDTPEAILNKTRHLGNDEVHIVWSEHNRDYRRD 1995

  Fly   557 MIASHFLHAFIVVQPIEPNTPHTRYKVSVTARDDVPFFGPTLPNPAVFRKGQEFKEFILTKLINA 621
            ::.:.|....||:.|::...    ::|:|..:.:||:|||......|  .|......:....|||
Mosquito  1996 ILPTEFCDVLIVIYPLKSGL----FRVTVNKKPEVPWFGPLSDEMVV--GGACLASLVRASAINA 2054

  Fly   622 ENACYKAEKFAKLEQRTRTSLLQNLCEELREKTRDFLGTDLSQTSAGSP---------TPET-PK 676
            ..|           :|:...|.|...|| |.::.|.:.....:.|....         .|:| .|
Mosquito  2055 SRA-----------KRSSLPLYQQYYEE-RNRSIDTVALRHRENSTFEDFTARIFCPIAPQTGGK 2107

  Fly   677 AESGSGGN------AGSRFIDTVKKALIMRVRSQSVDTGNGHGPGQTDKFSVNTKLGTLNSKKET 735
            ...|.||.      |||........|..:   :.::...:..||.:|               ...
Mosquito  2108 FGGGIGGGASAAAAAGSSIASGTNAAAPL---AAALIDHHSRGPSKT---------------WIH 2154

  Fly   736 HPEMQTPNLNTCSRTASKSSSKSKSSNESTSSSP-----------DITSRQANNNNTNSIGGHLP 789
            ||||..        ||.:.:.::.:|......||           .:...:.|.::..:.||.:
Mosquito  2155 HPEMVA--------TAREVTQQTLASVSLDQPSPRPLRKLHHPFKAVPKGKVNQHSIAAAGGSM- 2210

  Fly   790 QNGTGGGVVAAAVSAAQNGV---VAVATMSETSDDSSL 824
              .:.|.:..|.:|.|..|:   :..|.:|...:..:|
Mosquito  2211 --ASSGSIYGAGMSTASTGMSVPIGAAGVSTPPESPTL 2246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RapGAP1	NP_001097114.2	GoLoco	147..168	CDD:460481	0/20 (0%)
		Rap_GAP	460..639	CDD:460463	53/179 (30%)
LOC1273968	XP_061497090.1	None