Protein Alignment RapGAP1 and rap1gapl

DIOPT Version :9

• Sequence 1: NP_001097114.2
• Gene: RapGAP1 / 34032
• FlyBaseID: FBgn0264895
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: XP_005158249.1
• Gene: rap1gapl / 101884099
• ZFINID: ZDB-GENE-141212-231
• Length: 552
• Species: Danio rerio
• Alignment Length: 662
• Identity: 224/662 - (33%)
• Similarity: 310/662 - (46%)
• Gaps: 185/662 - (27%)

  Fly    96 SCEN------IDMLTEPLRRQHAFMANTQKQQPAGGGSGSGSVTHSPERLRGATTATQDLFELLE 154
            ||:.      :|:|..|          |.:.:|......|..||              :||.::|
Zfish    33 SCDEAVGHNILDVLDSP----------TSEAKPLTSVPSSQKVT--------------ELFAIIE 73

  Fly   155 RVQCSRLDDQRCVLPAYFSQNHHRGSNASEERVPQPHSPHDSHAHPHNGGLQHSGSRATLRHSMN 219
            ::|.||||:|||..|.
Zfish    74 KLQGSRLDEQRCEFPP------------------------------------------------- 89

  Fly   220 HSSSSTVSGSACSSTPASPQLSGVVSASGCQLLSNGHHYQSQSSVSSNSSIVSAIPASQRLLE-- 282
                                                                   |...|||:
Zfish    90 -------------------------------------------------------PLKTRLLKIG 99

  Fly   283 EALAKPAPYPMILLPLHGGYWMDGTEHECGYDARGNPLLPQTTWMAK----FETDDTAKCYRRFY 343
            :.|      |:||.|..||||:|....:   ....:|.|.|..:..:    .|.|..||.|:.|:
Zfish   100 DGL------PLILPPKSGGYWIDPPLDK---QVETSPTLSQGGFGLESYDIMERDSEAKVYQEFF 155

  Fly   344 AAREHSNLIGLDEQLGPILLSIKTENVANQEHMRILMRLRTGTMHELLPVSCLLPQPSPAKMAHT 408
            ..|.|.:....|..|||::||:..|...|:  :|:::|::..::|....||.....|:..::|..
Zfish   156 RHRYHHSFTACDPALGPLVLSVCLEEEENR--LRVILRMKECSIHGTFSVSLFQQFPTAVELAKM 218

  Fly   409 LNENITVEHFMPILCPKASQLISVYDEHVLVSHFKFGVLYQRYGQTTEEELFGNQQTSPAFDEFL 473
            |..|:.|..|..:...||.::|..:|||.:..:||||||||:.||.|||::..|.:.|..|.|||
Zfish   219 LCSNVNVMCFEAVSYLKAPEIIMAFDEHRVSQNFKFGVLYQKEGQLTEEDMLSNNEESEEFLEFL 283

  Fly   474 DVLGQRIRLKDHKGYRGGLDIQNGHTGDTAVYEVFKEREIMFHVSTLLPHTEGDPQQLQRKRHIG 538
            .:|||.:.|:...|:|||||:..|.||:.||:..|..|||||||:|.||.||||.||||||||||
Zfish   284 SILGQTVNLQGFTGFRGGLDVSRGQTGNEAVFTSFHGREIMFHVATKLPFTEGDTQQLQRKRHIG 348

  Fly   539 NDIVAIVFQETNTPFSPDMIASHFLHAFIVVQPIEPNTPHT-----RYKVSVTARDDVPFFGPTL 598
            |||||:|:||.:|||..|:|.|||||.||.|:.|:......     .::||||||:|||.|||.|
Zfish   349 NDIVALVYQEGHTPFISDVIRSHFLHCFIAVRRIKRENEGEGGDGGSFQVSVTAREDVPPFGPPL 413

  Fly   599 PNPAVFRKGQEFKEFILTKLINAENACYKAEKFAKLEQRTRTSLLQNLCEELREKTRDFLG---- 659
            |.|.:|.:|...:||:||||||||.:|||||||::||.|||:|||:.|..||..:::..||
Zfish   414 PTPPIFTEGSVLREFLLTKLINAEISCYKAEKFSRLELRTRSSLLEALRCELSSRSQCMLGEPSQ 478

  Fly   660 TDLSQTSAGSPTPETPKAESGSGGNAGSRFIDTVKKALIMRVRSQSVDT-----------GNGHG 713
            :.:..|..|...||      |.||     ||:..|:|:  ||||.|.||           |....
Zfish   479 SSIPLTEGGRSAPE------GGGG-----FIENFKRAI--RVRSHSFDTLGVPKKAAAVAGQRTK 530

  Fly   714 PGQTDKFSVNTK 725
            .|::|:.| ||:
Zfish   531 DGESDQTS-NTE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RapGAP1	NP_001097114.2	GoLoco	147..168	CDD:280368	11/20 (55%)
		Rap_GAP	460..639	CDD:280332	105/183 (57%)
rap1gapl	XP_005158249.1	GoLoco	67..87	CDD:214645	11/19 (58%)
		Rap_GAP	285..454	CDD:280332	99/168 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586367
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3686
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D163377at33208
OrthoFinder	1	1.000	-	-		FOG0002359
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15711
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810