Protein Alignment RapGAP1 and rap1gap2b

DIOPT Version :10

• Sequence 1: NP_001097114.2
• Gene: RapGAP1 / 34032
• FlyBaseID: FBgn0264895
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: XP_068071862.2
• Gene: rap1gap2b / 100170821
• ZFINID: ZDB-GENE-080722-11
• Length: 739
• Species: Danio rerio
• Alignment Length: 824
• Identity: 281/824 - (34%)
• Similarity: 402/824 - (48%)
• Gaps: 172/824 - (20%)

  Fly   151 ELLERVQCSRLDDQRCVLPAYFSQNHHRGSNASEERVPQPHSPHDSHAHPHNGGLQHSGSRATLR 215
            ||..||:|.|                 .|..|:...:                ||.|...:...|
Zfish     3 ELRSRVRCRR-----------------AGVRAAAALI----------------GLLHRSRKRCER 34

  Fly   216 HSMNHSSSS------TVSGSACSSTPASPQLSGVVSASGCQLLSNGHHYQSQSSVSSNSSIVSAI 274
            ..:....|.      |:|....|..|.||..:...:....|.      :.....:...|.:....
Zfish    35 RRLTEGDSQWKQELLTISNVPLSDCPHSPPRTAPPAVKSTQF------FDMLDKMEQVSEVEEMR 93

  Fly   275 PASQRL---------LEEALAKPAPYPMILLPLHGGYWMDGTE-------HECGY------DARG 317
            |  ||:         :||.|.:..|||.::||..||||::..|       .|.|:      |.|.
Zfish    94 P--QRVKDDYIPYPRIEEVLQRGEPYPQVILPQFGGYWIEDPEAPAAIANWENGFCDDDDEDGRN 156

  Fly   318 NPLLPQTTWMAKFETDDTAKCYRRFYAAREHSNLIGLDEQLGPILLSIKTENVANQEHMRILMRL 382
            :     ..:..|.|::...:.||:.:..|||.|........|.::||::.|.|..||::.|::|.
Zfish   157 S-----GEYGYKLESNFAIRAYRKHFLGREHLNFYCTASNHGNLVLSLRHEEVKEQEYLHIILRA 216

  Fly   383 RTGTMHELLPVSCLLPQPSPAKMAHTLNENITVEHFMPILCPKASQLISVYDEHVLVSHFKFGVL 447
            .:.|:::.:.::.|...||..::|..|.|:|....|.|:|.||.||||..||||.|.:.|||||:
Zfish   217 PSKTIYDRISLTGLTELPSVPQLAKLLCEDIVGLRFSPVLYPKGSQLIVNYDEHELNNTFKFGVI 281

  Fly   448 YQRYGQTTEEELFGNQQTSPAFDEFLDVLGQRIRLKDHKGYRGGLDIQNGHTGDTAVYEVFKERE 512
            ||::|||:|||||||.:.:|||.|||.|||..::|:|.||:|||||:.:|.||..:||.|||.:|
Zfish   282 YQKFGQTSEEELFGNSEETPAFTEFLRVLGDCVQLQDFKGFRGGLDVSHGQTGSQSVYTVFKGQE 346

  Fly   513 IMFHVSTLLPHTEGDPQQLQRKRHIGNDIVAIVFQETNTPFSPDMIASHFLHAFIVVQPIEPNTP 577
            :|||:||.||:.|||.|||||||||||||||.||||..|||.||||||:||||:|:||.....|.
Zfish   347 LMFHISTKLPYIEGDTQQLQRKRHIGNDIVAAVFQEEATPFVPDMIASNFLHAYILVQVENSGTD 411

  Fly   578 HTRYKVSVTARDDVPFFGPTLPNPAVFRKGQEFKEFILTKLINAENACYKAEKFAKLEQRTRTSL 642
            ...||||||||:|||.|||.||||.:|:||.||:||:||||||||.|||::.:|||||:||||.|
Zfish   412 EATYKVSVTAREDVPQFGPPLPNPPIFKKGPEFREFLLTKLINAELACYRSNRFAKLEERTRTEL 476

  Fly   643 LQNLCEELREKTRDFLGTDLSQTSAGSPTPETPKAESGSGGNAGSRFIDTVKKALIMRVRSQSVD 707
            |.||..||:::|:..||..|:        |:..:.|:|..|.    .::::|:|  |||||.|::
Zfish   477 LDNLHNELQKRTQSMLGHPLN--------PDEERMENGGHGG----ILESIKRA--MRVRSHSME 527

  Fly   708 T--------------GNG-----------HGPGQTDKFS--------------VNTKLG---TLN 730
            |              |.|           |...:..|.|              |..:.|   .|.
Zfish   528 TMVGTHKHGRCSPAAGAGVPTSLSGVSLTHSSSEAAKNSSPVTSSAKSPLKSPVKRRSGLFPRLY 592

  Fly   731 SKKETHPEMQTPNLNTCSRT--ASKSSSKSKSSNESTSSSPDITSRQANNNNTNSIGGHLPQNGT 793
            :..:..||..|.::....|:  ....|.:.||...|..|||:|.:.:..:.....:.|  |.:
Zfish   593 TSMDEQPERHTRSVLCDQRSLDCGHLSQEVKSETSSNPSSPEILNNERPSLKLQEVSG--PPD-- 653

  Fly   794 GGGVVAAAVSAAQNGVVAVATMSETSDDSSLNSVDLDPMMAHLDGGATYIDSDTGLESMSSAEAT 858
                 .:..|::.:...:.|...||.::...:.|.:.|.::.:.|
Zfish   654 -----ISRSSSSTSSFSSAAGEPETVEEKEPSGVQISPSLSPVFG-------------------- 693

  Fly   859 TKACSLCLDGVQS---TIMGSSPS---NETIVKIENLRQEVTRL 896
                ||..||..:   .||..||:   |:|..: .||:....||
Zfish   694 ----SLTTDGQAAGAPVIMCRSPTDFRNKTSPR-SNLKFRFDRL 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RapGAP1	NP_001097114.2	GoLoco	147..168	CDD:460481	6/16 (38%)
		Rap_GAP	460..639	CDD:460463	118/178 (66%)
rap1gap2b	XP_068071862.2	None