DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment santa-maria and scarb2b

DIOPT Version :9

Sequence 1:	NP_609121.2	Gene:	santa-maria / 34024	FlyBaseID:	FBgn0025697	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_009299911.1	Gene:	scarb2b / 564077	ZFINID:	ZDB-GENE-170406-1	Length:	523	Species:	Danio rerio

Alignment Length:	530	Identity:	156/530 - (29%)
Similarity:	264/530 - (49%)	Gaps:	42/530 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GIFGFCLGLFGILCGMFWVDLFDWIMH----KEMALAPDTRVYENWKSPPIDLSLDIYLYNWTNP 80
            |..|..|.|.||  .:|...||..::|    ||:.|...::|:..||:||..:.::.:.:|.|||
Zfish    12 GAAGALLLLAGI--ALFASGLFQTLIHNKLKKEITLTEGSKVFATWKNPPPPVYMEFFFFNVTNP 74

  Fly    81 EDFGNLSTKPILEQVGPYRFIERPDKVDIHWHPENASVTYRRRSLFYFDAAGSNGSLD-DEITTL 144
            |.|.....|..|.::|||.:.|...|.::.:......|......:|.|....|.|... |.:||:
Zfish    75 EAFLKGEAKARLSEMGPYTYREYRPKHNVSFVDNGTKVAAYTPKVFVFVPEKSVGDPSVDMVTTV 139

  Fly   145 NAVALSAAATAKYWPPVKRSLVDVGLKMYGAEMSVQKSIDELLFTGYNDAMIDVAMAMPIFGDEV 209
            |..|::.....|....:..|.:.:.:|..||||.:..::||||: |:.|.::....::....||.
Zfish   140 NIPAVAVMNRIKGAGFLVSSAMSLYMKSIGAEMFMTHTVDELLW-GFKDPLLTKLRSIKPETDEF 203

  Fly   210 KVPFDKFGWFYTRNGSADLTGVFNVFTGADQLAKLGQMHSWNYQENTGFF-DSYCGMTNGSAGE- 272
                  ||....:|||.|  |.|...||.......|::.:|..::...|: .:...|.||:.|.
Zfish   204 ------FGLMLHKNGSDD--GEFVYHTGEHNYLDYGRIFTWKGEKLMSFWKTNQSNMINGTDGSA 260

  Fly   273 FQPQHLKPGDSVGLFTPDMCRTIPLDYVETVDIEGLEGYKFSGGPRSV-DNGTQYPENLCFC--G 334
            |.| .|...:.:.:||.|:||:|.:.:.:.|:::|:..|:|: .||:| .:||..|||..||  .
Zfish   261 FHP-FLTKEERLDVFTADLCRSIHMRFEKEVEVKGIPAYRFT-PPRAVLASGTNNPENEGFCLTP 323

  Fly   335 GQCVPSGVMNISSCRFGSPVFMSYPHFFNADPYYPDQVEGLSPNQKDHEFYMVVQPSTGIPLEVA 399
            .:|:..||:::|.||.|:||.:|:|||...|..|...||||||..:.|:.::.:.|:.|:|:...
Zfish   324 KKCLDDGVLDVSVCRQGAPVVVSFPHFHLGDEKYVQAVEGLSPVHEQHQTFLDLNPTMGVPVRAM 388

  Fly   400 ARFQVNMLVEPIQGISLYTGIPRIFFPLVWFEQKVRITPDMADQL-KVLPIVMLSGHIFAGICLI 463
            .|.|:|:.:|.:.|..:...:....||:::..:.|.|....|::: |:|.:|.|..| |..|.:.
Zfish   389 KRAQINIHLERVTGFPMTRNLESTIFPIIFLNESVVIDNASAERIQKLLLVVTLVSH-FPLILVA 452

  Fly   464 VGITLLCWTPVQILLASCRNRRYDLRTKTKTNGQYKSRSQFSSAEELKSKASTLVCEKSVKGSPD 528
            :|:.||.   |.::||.   |.|..:|:.|         :|..||.....|.:  .:|....:|.
Zfish   453 LGVILLI---VAVILAV---RYYQNKTEVK---------RFDFAEAFHCTAPS--AKKDTSYAPV 500

  Fly   529 SSPLLEKGRK 538
            |:.:.::..|
Zfish   501 SAKVDDQDEK 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
santa-maria	NP_609121.2	CD36	23..474	CDD:279474	140/461 (30%)
scarb2b	XP_009299911.1	CD36	30..463	CDD:279474	135/447 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030